IL-33 facilitates rapid expulsion of the parasitic nematode Strongyloides ratti from the intestine via ILC2- and IL-9-driven mast cell activation

Parasitic helminths are sensed by the immune system via tissue-derived alarmins that promote the initiation of the appropriate type 2 immune responses. Here we establish the nuclear alarmin cytokine IL-33 as a non-redundant trigger of specifically IL-9-driven and mast cell-mediated immunity to the i...

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Detalles Bibliográficos
Autores principales: Meiners, Jana, Reitz, Martina, Rüdiger, Nikolas, Turner, Jan-Eric, Heepmann, Lennart, Rudolf, Lena, Hartmann, Wiebke, McSorley, Henry J., Breloer, Minka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7787685/
https://www.ncbi.nlm.nih.gov/pubmed/33351862
http://dx.doi.org/10.1371/journal.ppat.1009121

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