Amphiphilic Polymer-Modified Uniform CuFeSe(2) Nanoparticles for CT/MR Dual-Modal Imaging

Recently, magnetic photothermal nanomaterials have attracted much attention in the diagnosis and treatment of cancer. In this study, we developed the ultrasmall magnetic CuFeSe(2) nanoparticles for CT/MR dual-modal imaging. By controlling the reaction time and condition, CuFeSe(2) nanoparticles were...

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Detalles Bibliográficos
Autores principales: Wu, Min, Fu, Shaozhi, Shu, Jian, Yu, Kequan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7787810/
https://www.ncbi.nlm.nih.gov/pubmed/33456402
http://dx.doi.org/10.1155/2020/4891325
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author Wu, Min
Fu, Shaozhi
Shu, Jian
Yu, Kequan
author_facet Wu, Min
Fu, Shaozhi
Shu, Jian
Yu, Kequan
author_sort Wu, Min
collection PubMed
description Recently, magnetic photothermal nanomaterials have attracted much attention in the diagnosis and treatment of cancer. In this study, we developed the ultrasmall magnetic CuFeSe(2) nanoparticles for CT/MR dual-modal imaging. By controlling the reaction time and condition, CuFeSe(2) nanoparticles were synthesized by a simple directly aqueous method. After modification with copolymer methoxy polyethylene glycol-polycaprolactone (MPEG-PCL), the obtained MPEG-PCL@CuFeSe(2) nanoparticles showed excellent water solubility, colloidal stability, and biocompatibility. In addition, they also exhibited superparamagnetism and X-ray's characteristics. For these properties, they will become ideal nanomaterials for CT/MR dual-modal imaging.
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spelling pubmed-77878102021-01-14 Amphiphilic Polymer-Modified Uniform CuFeSe(2) Nanoparticles for CT/MR Dual-Modal Imaging Wu, Min Fu, Shaozhi Shu, Jian Yu, Kequan Contrast Media Mol Imaging Research Article Recently, magnetic photothermal nanomaterials have attracted much attention in the diagnosis and treatment of cancer. In this study, we developed the ultrasmall magnetic CuFeSe(2) nanoparticles for CT/MR dual-modal imaging. By controlling the reaction time and condition, CuFeSe(2) nanoparticles were synthesized by a simple directly aqueous method. After modification with copolymer methoxy polyethylene glycol-polycaprolactone (MPEG-PCL), the obtained MPEG-PCL@CuFeSe(2) nanoparticles showed excellent water solubility, colloidal stability, and biocompatibility. In addition, they also exhibited superparamagnetism and X-ray's characteristics. For these properties, they will become ideal nanomaterials for CT/MR dual-modal imaging. Hindawi 2020-12-30 /pmc/articles/PMC7787810/ /pubmed/33456402 http://dx.doi.org/10.1155/2020/4891325 Text en Copyright © 2020 Min Wu et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Wu, Min
Fu, Shaozhi
Shu, Jian
Yu, Kequan
Amphiphilic Polymer-Modified Uniform CuFeSe(2) Nanoparticles for CT/MR Dual-Modal Imaging
title Amphiphilic Polymer-Modified Uniform CuFeSe(2) Nanoparticles for CT/MR Dual-Modal Imaging
title_full Amphiphilic Polymer-Modified Uniform CuFeSe(2) Nanoparticles for CT/MR Dual-Modal Imaging
title_fullStr Amphiphilic Polymer-Modified Uniform CuFeSe(2) Nanoparticles for CT/MR Dual-Modal Imaging
title_full_unstemmed Amphiphilic Polymer-Modified Uniform CuFeSe(2) Nanoparticles for CT/MR Dual-Modal Imaging
title_short Amphiphilic Polymer-Modified Uniform CuFeSe(2) Nanoparticles for CT/MR Dual-Modal Imaging
title_sort amphiphilic polymer-modified uniform cufese(2) nanoparticles for ct/mr dual-modal imaging
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7787810/
https://www.ncbi.nlm.nih.gov/pubmed/33456402
http://dx.doi.org/10.1155/2020/4891325
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AT yukequan amphiphilicpolymermodifieduniformcufese2nanoparticlesforctmrdualmodalimaging

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