Cargando…

De Novo Acute Myeloid Leukemia with Combined CBFB-MYH11 and BCR-ABL1 Gene Rearrangements: A Case Report and Review of Literature

Acute myeloid leukemia (AML) with inv(16)(p13.1q22) resulting in CBFB-MYH11 fusion is associated with a favorable prognosis. The presence of a KIT mutation modifies it to an intermediate prognosis. Additionally, inv(16) can cooperate with other genetic aberrations to further increase cell proliferat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sethapati, Venkata Rakesh, Jabr, Ra'ed, Shune, Leyla, El Atrouni, Wissam, Gonzales, Patrick R., Cui, Wei, Golem, Shivani
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7787850/ https://www.ncbi.nlm.nih.gov/pubmed/33489389 http://dx.doi.org/10.1155/2020/8822670

Ejemplares similares

Disseminated Infection Due to Neocosmospora (Fusarium) falciformis in a Patient with Acute Myelogenous Leukemia
por: Jabr, Ra’ed, et al.
Publicado: (2022)

1602. Clostridium difficile Infection as a Predictor of Acute Graft vs. Host Disease Among Allogenic Stem Cell Transplant Recipients
por: Jabr, Ra’Ed, et al.
Publicado: (2018)

Ehrlichiosis mimicking acute leukemia
por: Jabr, Ra’ed, et al.
Publicado: (2022)

1711. Histoplasmosis-Associated Hemophagocytic Lymphohistiocytosis: A Case Series and Review of the Literature
por: Jabr, Ra’ed, et al.
Publicado: (2019)

Histoplasmosis-Associated Hemophagocytic Lymphohistiocytosis: A Review of the Literature
por: Jabr, Ra'ed, et al.
Publicado: (2019)

Primary peritoneal myeloid sarcoma in association with CBFB/MYH11 fusion
por: Kuhlman, Justin J., et al.
Publicado: (2021)

Runx1 is required for hematopoietic defects and leukemogenesis in Cbfb-MYH11 knockin mice
por: Hyde, R. Katherine, et al.
Publicado: (2015)

CBFB-MYH11 fusion transcripts distinguish acute myeloid leukemias with distinct molecular landscapes and outcomes
por: Huang, Benjamin J., et al.
Publicado: (2021)

bcr Rearrangement without juxtaposition of c-abl in chronic myelocytic leukemia
Publicado: (1985)

Heterogeneity of BCR-ABL rearrangement in patients with chronic myeloid leukemia in Pakistan
por: Tabassum, Najia, et al.
Publicado: (2014)

IL1RL1 is dynamically expressed on Cbfb-MYH11(+) leukemia stem cells and promotes cell survival
por: Wang, Yiqian, et al.
Publicado: (2019)

Gata2 deficiency delays leukemogenesis while contributing to aggressive leukemia phenotype in Cbfb-MYH11 knockin mice
por: Saida, Satoshi, et al.
Publicado: (2019)

Molecular dissection of a hyper-aggressive CBFB-MYH11/FLT3-ITD–positive acute myeloid leukemia
por: Lo Iudice, Gabriele, et al.
Publicado: (2022)

An unusual case of high hyperdiploid childhood ALL with cryptic BCR/ABL1 rearrangement
por: Lizcova, Libuse, et al.
Publicado: (2014)

BCR-ABL rearrangement and HLA antigens: a possible link to leukemia pathogenesis and immunotherapy
por: Giunta, Marina, et al.
Publicado: (2012)

CBFB-MYH11 Fusion Sequesters RUNX1 in Cytoplasm to Prevent DNMT3A Recruitment to Target Genes in AML
por: Liu, Peng, et al.
Publicado: (2021)

Comprehensive Mutation Profile in Acute Myeloid Leukemia Patients with RUNX1-RUNX1T1 or CBFB-MYH11 Fusions
por: Qin, Wei, et al.
Publicado: (2022)

Analytical study of RUNX1-RUNXT1, PML-RARA, CBFB-MYH11, BCR-ABL1(p210), and KMT2-MLLT3 in Mexican children with acute myeloid leukemia: A multicenter study of the Mexican interinstitutional group for the identification of the causes of childhood leukemia (MIGICCL)
por: Sepúlveda-Robles, Omar, et al.
Publicado: (2022)

Coexistence of p210(BCR-ABL) and CBFβ-MYH11 fusion genes in myeloid leukemia: A report of 4 cases
por: Wang, Yuan-Yuan, et al.
Publicado: (2017)

CBFB-MYH11 hypomethylation signature and PBX3 differential methylation revealed by targeted bisulfite sequencing in patients with acute myeloid leukemia
por: Hájková, Hana, et al.
Publicado: (2014)

Acute hepatitis-like presentation with cholestasis of CBFB–MYH11-positive acute myeloid leukemia in an adult male: a case report
por: Spinelli, Irene, et al.
Publicado: (2022)

Allosteric inhibition enhances the efficacy of ABL kinase inhibitors to target unmutated BCR-ABL and BCR-ABL-T315I
por: Mian, Afsar Ali, et al.
Publicado: (2012)

Targeting BCR-ABL(+) stem/progenitor cells and BCR-ABL-T315I mutant cells by effective inhibition of the BCR-ABL-Tyr177-GRB2 complex
por: Chen, Min, et al.
Publicado: (2017)

A Case of Acute Myeloid Leukemia With inv(16)(p13.1q22);CBFB-MYH11 Presenting With Faggot Cells
por: Kim, Jung-Ah, et al.
Publicado: (2021)

Persistence of chronic myelocytic leukemia despite deletion of rearranged bcr/c-abl sequences in blast crisis
Publicado: (1986)

The e8a2 fusion transcript in B lymphoblastic leukemia with BCR-ABL1 rearrangement
por: Kim, Min Jin, et al.
Publicado: (2012)

How to Improve Prognostication in Acute Myeloid Leukemia with CBFB-MYH11 Fusion Transcript: Focus on the Role of Molecular Measurable Residual Disease (MRD) Monitoring
por: Talami, Annalisa, et al.
Publicado: (2021)

BCR/ABL1 and BCR are under the transcriptional control of the MYC oncogene
por: Sharma, Nitesh, et al.
Publicado: (2015)

Pterostilbene downregulates BCR/ABL and induces apoptosis of T315I-mutated BCR/ABL-positive leukemic cells
por: Kawakami, Shohei, et al.
Publicado: (2022)

CNS Infection Mimicking Stroke
por: Jabr, Ra’ed, et al.
Publicado: (2020)

Scedosporium apiospermum fungemia successfully treated with voriconazole and terbinafine
por: Jabr, Ra’ed, et al.
Publicado: (2020)

EVI1 expression in childhood acute lymphoblastic leukaemia is not restricted to MLL and BCR/ABL rearrangements and is influenced by age
por: Stevens, A, et al.
Publicado: (2014)

Susceptibility Of Ph-Positive All To Tki Therapy Associated With Bcr-Abl Rearrangement Patterns: A Retrospective Analysis
por: Jing, Yu, et al.
Publicado: (2014)

Entire ABL1 Gene Deletion Without BCR/ABL1 Rearrangement in a Female Patient with B-Cell Precursor Acute Lymphoblastic Leukemia
por: Jiang, Yijing, et al.
Publicado: (2020)

BCR: a new target in resistance mediated by BCR/ABL-315I?
por: Haberbosch, Isabella, et al.
Publicado: (2016)

The novel anticancer agent JNJ-26854165 is active in chronic myeloid leukemic cells with unmutated BCR/ABL and T315I mutant BCR/ABL through promoting proteosomal degradation of BCR/ABL proteins
por: You, Liangshun, et al.
Publicado: (2016)

Expanding the Diversity of Allosteric Bcr-Abl Inhibitors
por: Deng, Xianming, et al.
Publicado: (2010)

An In-House Method for Molecular Monitoring of BCR-ABL
por: Sercan, Hakkı Ogün, et al.
Publicado: (2012)

Depression of oncogenecity by dephosphorylating and degrading BCR-ABL
por: Gao, Miao, et al.
Publicado: (2016)

Frequency of p190 and p210 BCR-ABL rearrangements and survival in Brazilian adult patients with acute lymphoblastic leukemia
por: de França Azevedo, Ilana, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_t9pf94nk7aacsprobl7t6dtsre