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PKN2 is involved in aggregation and spheroid formation of fibroblasts in suspension culture by regulating cell motility and N-cadherin expression

The role of Protein Kinase N2 (PKN2, also known as PRK2/PKNγ) in cell aggregate/spheroid formation in suspension culture was investigated using immortalized fibroblasts established from PKN2(flox/flox) mouse embryos. PKN2(flox/flox) cells formed cell aggregates in flat bottom low attachment well pla...

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Detalles Bibliográficos
Autores principales: Kubouchi, Koji, Mukai, Hideyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7787963/
https://www.ncbi.nlm.nih.gov/pubmed/33437883
http://dx.doi.org/10.1016/j.bbrep.2020.100895