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Flow cytometry analysis of anti-polyethylene glycol antibodies in human plasma()
Polyethylene glycol (PEG) is a biocompatible polymer used in biotherapeutics to increase bioavailability, reduce the frequency of administration, and optimize pharmacokinetics. Anti-PEG antibodies have been detected in healthy individuals and may decrease efficacy and alter the pharmacokinetics of P...
Autores principales: | Fang, Jia-Long, Beland, Frederick A., Tang, Yangshun, Roffler, Steve R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7787990/ https://www.ncbi.nlm.nih.gov/pubmed/33437656 http://dx.doi.org/10.1016/j.toxrep.2020.12.022 |
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