Cargando…

Subcutaneous Injection Performance in Yucatan Miniature Pigs with and without Human Hyaluronidase and Auto-injector Tolerability in Humans

Recombinant human hyaluronidase PH20 (rHuPH20) facilitates subcutaneous (SC) delivery of co-administered therapeutic agents by locally and transiently degrading hyaluronan in the SC space, and can be administered with therapeutics using a variety of devices. Two SC delivery studies were carried out...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shi, Galen H., Connor, Robert J., Collins, David S., Kang, David W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788039/ https://www.ncbi.nlm.nih.gov/pubmed/33409604 http://dx.doi.org/10.1208/s12249-020-01880-0

Ejemplares similares

Identifying a predictive relationship between maximal flow rate and viscosity for subcutaneous administration of macromolecules with recombinant human hyaluronidase PH20 in a miniature pig model
por: Connor, Robert J., et al.
Publicado: (2023)

Pharmacokinetic Compatibility Study of Lidocaine with EXPAREL in Yucatan Miniature Pigs
por: Richard, Brigitte M., et al.
Publicado: (2011)

Exploring the Genetic Signature of Body Size in Yucatan Miniature Pig
por: Kim, Hyeongmin, et al.
Publicado: (2015)

Targeted Disruption of LDLR Causes Hypercholesterolemia and Atherosclerosis in Yucatan Miniature Pigs
por: Davis, Bryan T., et al.
Publicado: (2014)

Long-Term Tolerability, Safety, and Efficacy of Recombinant Human Hyaluronidase-Facilitated Subcutaneous Infusion of Human Immunoglobulin for Primary Immunodeficiency
por: Wasserman, Richard L., et al.
Publicado: (2016)

Genome analysis of Yucatan miniature pigs to assess their potential as biomedical model animals
por: Kwon, Dae-Jin, et al.
Publicado: (2019)

Human immune reactivity of GGTA1/CMAH/A3GALT2 triple knockout Yucatan miniature pigs
por: Shim, Joohyun, et al.
Publicado: (2021)

Unintentional injection to the bone with a pediatric epinephrine auto-injector
por: Ibrahim, Mariam, et al.
Publicado: (2018)

Hyaluronidase Inhibitor-Incorporated Cross-Linked Hyaluronic Acid Hydrogels for Subcutaneous Injection
por: Kim, Min-Hwan, et al.
Publicado: (2021)

Analysis of Swine Leukocyte Antigen Haplotypes in Yucatan Miniature Pigs Used as Biomedical Model Animal
por: Choi, Nu-Ri, et al.
Publicado: (2016)

Clicker Training Accelerates Learning of Complex Behaviors but Reduces Discriminative Abilities of Yucatan Miniature Pigs
por: Paredes-Ramos, Pedro, et al.
Publicado: (2020)

Effects of supplemental creatine and guanidinoacetic acid on spatial memory and the brain of weaned Yucatan miniature pigs
por: Robinson, Jason L., et al.
Publicado: (2020)

The Effects of an Osteoarthritic Joint Environment on ACL Damage and Degeneration: A Yucatan Miniature Pig Model
por: Schwartz, Elias, et al.
Publicado: (2023)

Comparative Pharmacokinetics and Insulin Action for Three Rapid-Acting Insulin Analogs Injected Subcutaneously With and Without Hyaluronidase
por: Morrow, Linda, et al.
Publicado: (2013)

Production of Multiple Transgenic Yucatan Miniature Pigs Expressing Human Complement Regulatory Factors, Human CD55, CD59, and H-Transferase Genes
por: Jeong, Young-Hee, et al.
Publicado: (2013)

Development and characterization of a Yucatan miniature biomedical pig permanent middle cerebral artery occlusion stroke model
por: Platt, Simon R, et al.
Publicado: (2014)

Hyaluronidase facilitated subcutaneous immunoglobulin in primary immunodeficiency
por: Jolles, Stephen
Publicado: (2013)

Prescribing of adrenaline auto-injectors
por: Kahlon, Gurnaaz Kaur
Publicado: (2015)

Hyaluronidases in Human Diseases
por: Kaul, Aditya, et al.
Publicado: (2021)

Pediatric Epinephrine Auto-injector Accident Without Digital Ischemia
por: Shapiro, Alex L, et al.
Publicado: (2019)

Satisfaction with Subcutaneous Golimumab and its Auto-Injector among Rheumatoid Arthritis Patients with Inadequate Response to Adalimumab or Etanercept
por: Dehoratius, Raphael J., et al.
Publicado: (2018)

Prescribing adrenaline auto-injectors in Slovenian children
por: Vesel, Tina, et al.
Publicado: (2015)

Mistaking an Auto-injector for a Ballpoint Pen
por: Maeda, Atsuo, et al.
Publicado: (2020)

Global disparities in availability of epinephrine auto-injectors
por: Tanno, Luciana Kase, et al.
Publicado: (2023)

No excessive mutations in transcription activator-like effector nuclease-mediated α-1,3-galactosyltransferase knockout Yucatan miniature pigs
por: Choi, Kimyung, et al.
Publicado: (2020)

Unintentional Epinephrine Auto-Injector Maxillofacial Injury in a Pediatric Patient
por: David, Jason, et al.
Publicado: (2022)

Subcutaneous administration of rituximab (MabThera) and trastuzumab (Herceptin) using hyaluronidase
por: Shpilberg, O, et al.
Publicado: (2013)

Guanidinoacetate Is More Effective than Creatine at Enhancing Tissue Creatine Stores while Consequently Limiting Methionine Availability in Yucatan Miniature Pigs
por: McBreairty, Laura E., et al.
Publicado: (2015)

Comparison of the robustness and functionality of three adrenaline auto-injectors
por: Schwirtz, Andreas, et al.
Publicado: (2012)

An open-label trial of alsuma auto-injector for migraine
por: Ramos, E, et al.
Publicado: (2013)

Adrenaline auto-injector prescription and patients’ administration proficiency
por: Amaral, Luis, et al.
Publicado: (2015)

Update on the usage and safety of epinephrine auto-injectors, 2017
por: Posner, Larry S, et al.
Publicado: (2017)

Development and usability of a new subcutaneous auto-injector device to administer hydroxyprogesterone caproate to reduce the risk of recurrent preterm birth
por: Travanty, Michael N, et al.
Publicado: (2018)

Use of Auto-Injector for Methotrexate Subcutaneous Self-Injections: High Satisfaction Level and Good Compliance in SELF-I Study, a Randomized, Open-Label, Parallel Group Study
por: Saraux, Alain, et al.
Publicado: (2018)

Safe and Effective Subcutaneous Self-Injection of Bimekizumab with Safety Syringe and Auto-Injector Devices: Results from a Multicenter, Randomized, Open-Label Study in Patients with Psoriatic Arthritis
por: Kivitz, Alan, et al.
Publicado: (2023)

Significantly delayed polyglactin 910 suture-related pseudoinfection in a Yucatan pig
por: Collins, Dalis, et al.
Publicado: (2020)

ENHANZE(®) drug delivery technology: a novel approach to subcutaneous administration using recombinant human hyaluronidase PH20
por: Locke, Kenneth W., et al.
Publicado: (2019)

Subcutaneous daratumumab and hyaluronidase-fihj in newly diagnosed or relapsed/refractory multiple myeloma
por: Sanchez, Larysa, et al.
Publicado: (2021)

The Additional Effect of Hyaluronidase in Lumbar Interlaminar Epidural Injection
por: Kim, Sang Beom, et al.
Publicado: (2011)

Acute urticaria caused by the injection of goat-derived hyaluronidase
por: Kim, Joo-Hee, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_nf7lhh5ltptj3hjhp8ulu8rqg7