Cargando…

WLS-Wnt signaling promotes neuroendocrine prostate cancer

Neuroendocrine prostate cancer (NEPC) is a lethal prostate cancer subtype arising as a consequence of more potent androgen receptor (AR) targeting in castration-resistant prostate cancer (CRPC). Its molecular pathogenesis remains elusive. Here, we report that the Wnt secretion mediator Wntless (WLS)...

Descripción completa

Detalles Bibliográficos
Autores principales: Bland, Tyler, Wang, Jing, Yin, Lijuan, Pu, Tianjie, Li, Jingjing, Gao, Jin, Lin, Tzu-Ping, Gao, Allen C., Wu, Boyang Jason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788232/
https://www.ncbi.nlm.nih.gov/pubmed/33437943
http://dx.doi.org/10.1016/j.isci.2020.101970