Germline variants are associated with increased primary melanoma tumor thickness at diagnosis

Germline genetic variants have been identified, which predispose individuals and families to develop melanoma. Tumor thickness is the strongest predictor of outcome for clinically localized primary melanoma patients. We sought to determine whether there is a heritable genetic contribution to variati...

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Detalles Bibliográficos
Autores principales: Mangantig, Ernest, MacGregor, Stuart, Iles, Mark M, Scolyer, Richard A, Cust, Anne E, Hayward, Nicholas K, Montgomery, Grant W, Duffy, David L, Thompson, John F, Henders, Anjali, Bowdler, Lisa, Rowe, Casey, Cadby, Gemma, Mann, Graham J, Whiteman, David C, Long, Georgina V, Ward, Sarah V, Khosrotehrani, Kiarash, Barrett, Jennifer H, Law, Matthew H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Association Studies Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788289/
https://www.ncbi.nlm.nih.gov/pubmed/33410475
http://dx.doi.org/10.1093/hmg/ddaa222

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