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Harnessing technology and portability to conduct molecular epidemiology of endemic pathogens in resource-limited settings

Improvements in genetic and genomic technology have enabled field-deployable molecular laboratories and these have been deployed in a variety of epidemics that capture headlines. In this editorial, we highlight the importance of building physical and personnel capacity in low and middle income count...

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Detalles Bibliográficos
Autores principales: Faust, Christina L, Brunker, Kirstyn, Ajambo, Diana, Ryan, Mary, Moses, Arinaitwe, Rowel, Candia, Wangoola, Robert Mandela, Wampande, Eddie M, Guma, Andrew, Adriko, Moses, Lamberton, Poppy H L, Tukahebwa, Edridah M, Mugenyi, Albert, Waiswa, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788292/
https://www.ncbi.nlm.nih.gov/pubmed/32945867
http://dx.doi.org/10.1093/trstmh/traa086
Descripción
Sumario:Improvements in genetic and genomic technology have enabled field-deployable molecular laboratories and these have been deployed in a variety of epidemics that capture headlines. In this editorial, we highlight the importance of building physical and personnel capacity in low and middle income countries to deploy these technologies to improve diagnostics, understand transmission dynamics and provide feedback to endemic communities on actionable timelines. We describe our experiences with molecular field research on schistosomiasis, trypanosomiasis and rabies and urge the wider tropical medicine community to embrace these methods and help build capacity to benefit communities affected by endemic infectious diseases.