Redox activation of ATM enhances GSNOR translation to sustain mitophagy and tolerance to oxidative stress

The denitrosylase S‐nitrosoglutathione reductase (GSNOR) has been suggested to sustain mitochondrial removal by autophagy (mitophagy), functionally linking S‐nitrosylation to cell senescence and aging. In this study, we provide evidence that GSNOR is induced at the translational level in response to...

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Detalles Bibliográficos
Autores principales: Cirotti, Claudia, Rizza, Salvatore, Giglio, Paola, Poerio, Noemi, Allega, Maria Francesca, Claps, Giuseppina, Pecorari, Chiara, Lee, Ji‐Hoon, Benassi, Barbara, Barilà, Daniela, Robert, Caroline, Stamler, Jonathan S, Cecconi, Francesco, Fraziano, Maurizio, Paull, Tanya T, Filomeni, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788447/
https://www.ncbi.nlm.nih.gov/pubmed/33245190
http://dx.doi.org/10.15252/embr.202050500

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