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A splicing factor switch controls hematopoietic lineage specification of pluripotent stem cells

Alternative splicing (AS) leads to transcriptome diversity in eukaryotic cells and is one of the key regulators driving cellular differentiation. Although AS is of crucial importance for normal hematopoiesis and hematopoietic malignancies, its role in early hematopoietic development is still largely...

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Detalles Bibliográficos
Autores principales: Li, Yapu, Wang, Ding, Wang, Hongtao, Huang, Xin, Wen, Yuqi, Wang, BingRui, Xu, Changlu, Gao, Jie, Liu, Jinhua, Tong, Jingyuan, Wang, Mengge, Su, Pei, Ren, Sirui, Ma, Feng, Li, Hong‐Dong, Bresnick, Emery H, Zhou, Jiaxi, Shi, Lihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788460/
https://www.ncbi.nlm.nih.gov/pubmed/33319461
http://dx.doi.org/10.15252/embr.202050535