Cross-talk between the calcium channel TRPV4 and reactive oxygen species interlocks adhesive and degradative functions of invadosomes

Invadosomes support cell invasion by coupling both acto-adhesive and extracellular matrix degradative functions, which are apparently antagonistic. β1-integrin dynamics regulate this coupling, but the actual sensing mechanism and effectors involved have not yet been elucidated. Using genetic and rev...

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Detalles Bibliográficos
Autores principales: Vellino, Sanela, Oddou, Christiane, Rivier, Paul, Boyault, Cyril, Hiriart-Bryant, Edwige, Kraut, Alexandra, Martin, René, Coute, Yohann, Knölker, Hans-Joachim, Valverde, Miguel A., Albigès-Rizo, Corinne, Destaing, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788461/
https://www.ncbi.nlm.nih.gov/pubmed/33399853
http://dx.doi.org/10.1083/jcb.201910079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788461/
https://www.ncbi.nlm.nih.gov/pubmed/33399853
http://dx.doi.org/10.1083/jcb.201910079

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