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Polo-like kinase 1 independently controls microtubule-nucleating capacity and size of the centrosome
Centrosomes are composed of a centriolar core surrounded by a pericentriolar material (PCM) matrix that docks microtubule-nucleating γ-tubulin complexes. During mitotic entry, the PCM matrix increases in size and nucleating capacity in a process called centrosome maturation. Polo-like kinase 1 (PLK1...
Autores principales: | Ohta, Midori, Zhao, Zhiling, Wu, Di, Wang, Shaohe, Harrison, Jennifer L., Gómez-Cavazos, J. Sebastián, Desai, Arshad, Oegema, Karen F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788462/ https://www.ncbi.nlm.nih.gov/pubmed/33399854 http://dx.doi.org/10.1083/jcb.202009083 |
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