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The Effects of Tofacitinib-Mediated Janus Kinase/Signal Transducers and Activators of the Transcription Signal Pathway Inhibition on Collagen Biosynthesis in Hepatic and Skin Fibroblast Cell Culture

OBJECTIVES: This study aims to investigate the effects of Janus kinase/signal transducers and activators of the transcription (JAK/STAT) pathway inhibition on collagen biosynthesis in fibroblast cell culture by tofacitinib. MATERIALS AND METHODS: BJ-CRL-1474® (skin) and BRL3A® (hepatic) fibroblast c...

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Detalles Bibliográficos
Autores principales: ŞAHİN, Mehtap, AYDIN, Hüseyin, ALTUN, Ahmet, DERİN, Mehmet Emin, ŞAHİN, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Turkish League Against Rheumatism 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788643/
https://www.ncbi.nlm.nih.gov/pubmed/33458657
http://dx.doi.org/10.46497/ArchRheumatol.2020.7568

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