Cargando…
The Effects of Tofacitinib-Mediated Janus Kinase/Signal Transducers and Activators of the Transcription Signal Pathway Inhibition on Collagen Biosynthesis in Hepatic and Skin Fibroblast Cell Culture
OBJECTIVES: This study aims to investigate the effects of Janus kinase/signal transducers and activators of the transcription (JAK/STAT) pathway inhibition on collagen biosynthesis in fibroblast cell culture by tofacitinib. MATERIALS AND METHODS: BJ-CRL-1474® (skin) and BRL3A® (hepatic) fibroblast c...
Autores principales: | ŞAHİN, Mehtap, AYDIN, Hüseyin, ALTUN, Ahmet, DERİN, Mehmet Emin, ŞAHİN, Ali |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Turkish League Against Rheumatism
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788643/ https://www.ncbi.nlm.nih.gov/pubmed/33458657 http://dx.doi.org/10.46497/ArchRheumatol.2020.7568 |
Ejemplares similares
-
Idiopathic erythema multiforme: Evidence of underlying Janus kinase–signal transducer and activator of transcription activation and successful treatment with tofacitinib
por: Damsky, William, et al.
Publicado: (2016) -
Can Calprotectin Show Subclinical Inflammation in Familial Mediterranean Fever Patients?
por: Asan, Gökmen, et al.
Publicado: (2020) -
Janus kinases and signal transducers and activators of transcription: their roles in cytokine signaling, development and immunoregulation
por: Ortmann, Robert A, et al.
Publicado: (2000) -
Role of Janus kinase 1 and signal transducer and activator of transcription 3 in vitiligo
por: Samaka, Rehab M, et al.
Publicado: (2019) -
Role of Janus Kinase/Signal Transducers and Activators of Transcription in the Pathogenesis of Pancreatitis and Pancreatic Cancer
por: Yu, Ji Hoon, et al.
Publicado: (2012)