Qualitative and quantitative comparison of cell-free DNA and cell-free fetal DNA isolation by four (semi-)automated extraction methods: impact in two clinical applications: chimerism quantification and noninvasive prenatal diagnosis

BACKGROUND: Non-invasive molecular analysis of cell-free DNA (cfDNA) became a sensitive biomarker for monitoring organ transplantation or for detection of fetal DNA (cffDNA) in noninvasive prenatal test. In this study, we compared the efficiencies of four (semi)-automated cfDNA isolation instruments...

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Detalles Bibliográficos
Autores principales: Pedini, Pascal, Graiet, Hajer, Laget, Laurine, Filosa, Lugdivine, Chatron, Jade, Cherouat, Nicem, Chiaroni, Jacques, Hubert, Lucas, Frassati, Coralie, Picard, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788686/
https://www.ncbi.nlm.nih.gov/pubmed/33407582
http://dx.doi.org/10.1186/s12967-020-02671-8

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