The M310T mutation in the GATA4 gene is a novel pathogenic target of the familial atrial septal defect

BACKGROUND: Although most cases of atrial septal defect (ASD) are sporadic, familial cases have been reported, which may be caused by mutation of transcription factor GATA binding protein 4 (GATA4). Herein we combined whole-exome sequencing and bioinformatics strategies to identify a novel mutation...

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Detalles Bibliográficos
Autores principales: Bu, Haisong, Sun, Guowen, Zhu, Yun, Yang, Yifeng, Tan, Zhiping, Zhao, Tianli, Hu, Shijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788758/
https://www.ncbi.nlm.nih.gov/pubmed/33413087
http://dx.doi.org/10.1186/s12872-020-01822-5

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