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PlGF knockdown attenuates hypoxia-induced stimulation of cell proliferation and glycolysis of lung adenocarcinoma through inhibiting Wnt/β-catenin pathway
BACKGROUND: Angiogenic placental growth factor (PlGF) plays a role in hypoxia-induced angiogenesis. Here, we aimed to investigate the biological roles of PlGF in cell proliferation and glycolysis of lung adenocarcinoma (LUAD) and the underlying molecular mechanisms. METHODS: PlGF was knocked down in...
Autores principales: | Zhang, Wei, Zhang, Yanwei, Zhou, Wensheng, Qian, Fangfei, Hu, Minjuan, Chen, Ya, Lu, Jun, Lou, Yuqing, Han, Baohui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788771/ https://www.ncbi.nlm.nih.gov/pubmed/33407494 http://dx.doi.org/10.1186/s12935-020-01714-w |
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