Cargando…

Immune responses to azacytidine in animal models of inflammatory disorders: a systematic review

Inflammatory disorders like diabetes, systemic lupus erythematodes, inflammatory lung diseases, rheumatoid arthritis and multiple sclerosis, but also rejection of transplanted organs and GvHD, form a major burden of disease. Current classes of immune suppressive drugs to treat these disorders are ne...

Descripción completa

Detalles Bibliográficos
Autores principales:	Landman, Sija, van der Horst, Chiel, van Erp, Piet E. J., Joosten, Irma, de Vries, Rob, Koenen, Hans J. P. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788785/ https://www.ncbi.nlm.nih.gov/pubmed/33407530 http://dx.doi.org/10.1186/s12967-020-02615-2

Ejemplares similares

Intradermal injection of low dose human regulatory T cells inhibits skin inflammation in a humanized mouse model
por: Landman, Sija, et al.
Publicado: (2018)

DNA Methyltransferase Inhibition Promotes Th1 Polarization in Human CD4(+)CD25(high) FOXP3(+) Regulatory T Cells but Does Not Affect Their Suppressive Capacity
por: Landman, Sija, et al.
Publicado: (2018)

A TNFR2-Agonist Facilitates High Purity Expansion of Human Low Purity Treg Cells
por: He, Xuehui, et al.
Publicado: (2016)

Azacytidine Treatment for VEXAS Syndrome
por: Raaijmakers, Marc H. G. P., et al.
Publicado: (2021)

The gut microbiome as mediator between diet and its impact on immune function
por: Shi, Huiqing, et al.
Publicado: (2022)

Successful Regulatory T Cell-Based Therapy Relies on Inhibition of T Cell Effector Function and Enrichment of FOXP3+ Cells in a Humanized Mouse Model of Skin Inflammation
por: Landman, S., et al.
Publicado: (2020)

Burn-injured skin is marked by a prolonged local acute inflammatory response of innate immune cells and pro-inflammatory cytokines
por: Mulder, Patrick P.G., et al.
Publicado: (2022)

Development of an Oral Form of Azacytidine: 2′3′5′Triacetyl-5-Azacytidine
por: Ziemba, Amy, et al.
Publicado: (2011)

Alterations of immune response of non-small cell lung cancer with Azacytidine
por: Wrangle, John, et al.
Publicado: (2013)

The Architecture of Circulating Immune Cells Is Dysregulated in People Living With HIV on Long Term Antiretroviral Treatment and Relates With Markers of the HIV-1 Reservoir, Cytomegalovirus, and Microbial Translocation
por: Van de Wijer, Lisa, et al.
Publicado: (2021)

Azacytidine (Vidaza®) in the treatment of myelodysplastic syndromes
por: Raj, Kavita, et al.
Publicado: (2006)

Chronic HIV infection induces transcriptional and functional reprogramming of innate immune cells
por: van der Heijden, Wouter A., et al.
Publicado: (2021)

The number of CCR5 expressing CD4+ T lymphocytes is lower in HIV-infected long-term non-progressors with viral control compared to normal progressors: a cross-sectional study
por: Meijerink, Hinta, et al.
Publicado: (2014)

Teriflunomide restores 5-azacytidine sensitivity via activation of pyrimidine salvage in 5-azacytidine-resistant leukemia cells
por: Imanishi, Satoshi, et al.
Publicado: (2017)

5-Azacytidine Potentiates Anti-tumor Immunity in a Model of Pancreatic Ductal Adenocarcinoma
por: Ebelt, Nancy D., et al.
Publicado: (2020)

Clinical Grade Treg: GMP Isolation, Improvement of Purity by CD127(pos) Depletion, Treg Expansion, and Treg Cryopreservation
por: Peters, Jorieke H., et al.
Publicado: (2008)

Immunological Monitoring of Renal Transplant Recipients to Predict Acute Allograft Rejection Following the Discontinuation of Tacrolimus
por: Kreijveld, Ellen, et al.
Publicado: (2008)

5-Azacytidine-Mediated Modulation of the Immune Microenvironment in Murine Acute Myeloid Leukemia
por: Ebelt, Nancy D., et al.
Publicado: (2022)

Changes in peripheral immune cell numbers and functions in octogenarian walkers – an acute exercise study
por: van der Geest, Kornelis S. M., et al.
Publicado: (2017)

Humanized Mouse Model of Skin Inflammation Is Characterized by Disturbed Keratinocyte Differentiation and Influx of IL-17A Producing T Cells
por: de Oliveira, Vivian L., et al.
Publicado: (2012)

Ex Vivo Generation of Human Alloantigen-Specific Regulatory T Cells from CD4(pos)CD25(high) T Cells for Immunotherapy
por: Peters, Jorieke H., et al.
Publicado: (2008)

An Autocrine TNFα–Tumor Necrosis Factor Receptor 2 Loop Promotes Epigenetic Effects Inducing Human Treg Stability In Vitro
por: Urbano, Paulo C. M., et al.
Publicado: (2018)

Metabolic Pathways Involved in Regulatory T Cell Functionality
por: Kempkes, Rosalie W. M., et al.
Publicado: (2019)

5-Azacytidine Promotes an Inhibitory T-Cell Phenotype and Impairs Immune Mediated Antileukemic Activity
por: Stübig, Thomas, et al.
Publicado: (2014)

Increased dermal expression of chromatin-associated protein HMGB1 and concomitant T-cell expression of the DNA RAGE in patients with psoriasis vulgaris
por: Strohbuecker, Lisa, et al.
Publicado: (2019)

The prognostic significance of chromosome 17 abnormalities in patients with myelodysplastic syndrome treated with 5‐azacytidine: Results from the Hellenic 5‐azacytidine registry
por: Diamantopoulos, Panagiotis, et al.
Publicado: (2019)

Thyrotrophin and thyroxine support immune homeostasis in humans
por: Jaeger, Martin, et al.
Publicado: (2021)

Single CD28 stimulation induces stable and polyclonal expansion of human regulatory T cells
por: He, Xuehui, et al.
Publicado: (2017)

Cytogenetic effect of 5-azacytidine in patients with hematological malignancies
por: Tsuda, Jessica Romy, et al.
Publicado: (2011)

CNS Involvement in AML Patient Treated with 5-Azacytidine
por: Vasilatou, Diamantina, et al.
Publicado: (2014)

Suppressing nonsense—a surprising function for 5-azacytidine
por: Shao, Ada, et al.
Publicado: (2014)

Comment on “5-Azacytidine Promotes an Inhibitory T-Cell Phenotype and Impairs Immune Mediated Antileukemic Activity”
por: Frøsig, Thomas Mørch, et al.
Publicado: (2015)

A Comparative Analysis of 5-Azacytidine- and Zebularine-Induced DNA Demethylation
por: Griffin, Patrick T., et al.
Publicado: (2016)

Targeted plasma proteomics reveals upregulation of distinct inflammatory pathways in people living with HIV
por: Vadaq, Nadira, et al.
Publicado: (2022)

Long-term development of post-traumatic stress symptoms and associated risk factors in military service members deployed to Afghanistan: Results from the PRISMO 10-year follow-up
por: van der Wal, Sija J., et al.
Publicado: (2020)

Treatment of Chronic Myelomonocytic Leukemia with 5-Azacytidine: Case Reports
por: Rohon, Peter, et al.
Publicado: (2012)

Effects of 5-Azacytidine on Growth and Hypocrellin Production of Shiraia bambusicola
por: Ma, Yan Jun, et al.
Publicado: (2018)

A cat with myelodysplastic syndrome by administration of the methylation inhibitor Azacytidine
por: HISASUE, Masaharu, et al.
Publicado: (2021)

Azacytidine and Venetoclax in Relapsed and Refractory Patients With Angioimmunoblastic T-cell Lymphoma
por: Laribi, Kamel, et al.
Publicado: (2022)

Priming Leukemia with 5-Azacytidine Enhances CAR T Cell Therapy
por: Xu, Ning, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_pjo72hblsl8vgp3irk3ieljhtn