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Construction and characterization of a novel glucose dehydrogenase-leucine dehydrogenase fusion enzyme for the biosynthesis of l-tert-leucine

BACKGROUND: Biosynthesis of l-tert-leucine (l-tle), a significant pharmaceutical intermediate, by a cofactor regeneration system friendly and efficiently is a worthful goal all the time. The cofactor regeneration system of leucine dehydrogenase (LeuDH) and glucose dehydrogenase (GDH) has showed grea...

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Detalles Bibliográficos
Autores principales:	Liao, Langxing, Zhang, Yonghui, Wang, Yali, Fu, Yousi, Zhang, Aihui, Qiu, Ruodian, Yang, Shuhao, Fang, Baishan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788806/ https://www.ncbi.nlm.nih.gov/pubmed/33407464 http://dx.doi.org/10.1186/s12934-020-01501-2

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