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Acute IL-1RA treatment suppresses the peripheral and central inflammatory response to spinal cord injury

BACKGROUND: The acute phase response (APR) to CNS insults contributes to the overall magnitude and nature of the systemic inflammatory response. Aspects of this response are thought to drive secondary inflammatory pathology at the lesion site, and suppression of the APR can therefore afford some neu...

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Detalles Bibliográficos
Autores principales: Yates, Abi G., Jogia, Trisha, Gillespie, Ellen R., Couch, Yvonne, Ruitenberg, Marc J., Anthony, Daniel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788822/
https://www.ncbi.nlm.nih.gov/pubmed/33407641
http://dx.doi.org/10.1186/s12974-020-02050-6