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Acute IL-1RA treatment suppresses the peripheral and central inflammatory response to spinal cord injury
BACKGROUND: The acute phase response (APR) to CNS insults contributes to the overall magnitude and nature of the systemic inflammatory response. Aspects of this response are thought to drive secondary inflammatory pathology at the lesion site, and suppression of the APR can therefore afford some neu...
Autores principales: | Yates, Abi G., Jogia, Trisha, Gillespie, Ellen R., Couch, Yvonne, Ruitenberg, Marc J., Anthony, Daniel C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788822/ https://www.ncbi.nlm.nih.gov/pubmed/33407641 http://dx.doi.org/10.1186/s12974-020-02050-6 |
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