Which prognostic marker is responsible for the clinical heterogeneity in CLL with 13q deletion?

BACKGROUND: Deletion of 13q14 [del(13q)] is the most common cytogenetic change (50%) in chronic lymphoblastic leukemia (CLL), and it is a good prognostic factor if it is detected as a sole aberration by FISH. However, it is observed the clinical course of CLL cases with del(13q) are quite heterogene...

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Detalles Bibliográficos
Autores principales: Durak Aras, Beyhan, Isik, Sevgi, Uskudar Teke, Hava, Aslan, Abdulvahap, Yavasoglu, Filiz, Gulbas, Zafer, Demirkan, Fatih, Ozen, Hulya, Cilingir, Oguz, Inci, Nur Sena, Gunden, Gulcin, Bulduk, Tuba, Erzurumluoglu Gokalp, Ebru, Kocagil, Sinem, Artan, Sevilhan, Akay, Olga Meltem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788884/
https://www.ncbi.nlm.nih.gov/pubmed/33407772
http://dx.doi.org/10.1186/s13039-020-00522-1

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