A novel somatic BRCA2 point mutation in a metastatic pancreatic cancer patient: a case report

BACKGROUND: In addition to ovarian and breast cancers, loss-of-function mutations in BRCA1 and BRCA2 genes are also linked to an increased risk of pancreatic cancer, with ~ 4 to 7% of pancreatic cancer patients harboring germline BRCA mutations. Most BRCA alterations in pancreatic cancer are frame-s...

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Detalles Bibliográficos
Autores principales: Wang, Deqiang, Guan, Ruting, Tao, Qing, Liu, Sisi, Yu, Man, Li, Xiaoqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788890/
https://www.ncbi.nlm.nih.gov/pubmed/33407459
http://dx.doi.org/10.1186/s12920-020-00850-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788890/
https://www.ncbi.nlm.nih.gov/pubmed/33407459
http://dx.doi.org/10.1186/s12920-020-00850-6

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