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Adapting the randomised controlled trial (RCT) for precision medicine: introducing the nested-precision RCT (npRCT)
Adaptations to the gold standard randomised controlled trial (RCT) have been introduced to decrease trial costs and avoid high sample sizes. To facilitate development of precision medicine algorithms that aim to optimise treatment allocation for individual patients, we propose a new RCT adaptation t...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788903/ https://www.ncbi.nlm.nih.gov/pubmed/33407710 http://dx.doi.org/10.1186/s13063-020-04965-0 |