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Pretreatment with intestinal trefoil factor alleviates stress-induced gastric mucosal damage via Akt signaling

BACKGROUND: Stress-related gastric mucosal damage or ulcer remains an unsolved issue for critically ill patients. Stress ulcer prophylaxis has been part of routine intensive care, but uncertainty and controversy still exist. Co-secreted with mucins, intestinal trefoil factor (ITF) is reported to pro...

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Detalles Bibliográficos
Autores principales: Huang, Yun, Wang, Meng-Meng, Yang, Zhi-Zhou, Ren, Yi, Zhang, Wei, Sun, Zhao-Rui, Nie, Shi-Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789054/
https://www.ncbi.nlm.nih.gov/pubmed/33505140
http://dx.doi.org/10.3748/wjg.v26.i48.7619