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JNK-IN-8 treatment alleviates lipopolysaccharide-induced acute lung injury via suppression of inflammation and oxidative stress regulated by JNK/NF-κB signaling

JNK serves critical roles in numerous types of inflammation- and oxidative stress-induced disease, including acute lung injury (ALI). JNK-IN-8 is the first irreversible JNK inhibitor that has been described. However, whether JNK-IN-8 can prevent lipopolysaccharide (LPS)-induced ALI by inhibiting JNK...

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Detalles Bibliográficos
Autores principales:	Du, Jingxian, Wang, Gaojian, Luo, Huanyu, Liu, Na, Xie, Junran
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789102/ https://www.ncbi.nlm.nih.gov/pubmed/33355369 http://dx.doi.org/10.3892/mmr.2020.11789

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