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Effects of normobaric cyclic hypoxia exposure on mesenchymal stem-cell differentiation–pilot study on bone parameters in elderly

BACKGROUND: Mesenchymal stem cells (MSC) of bone marrow are the progenitor of osteoblasts and adipocytes. MSC tend to differentiate into adipocytes, instead of osteoblasts, with aging. This favors the loss of bone mass and development of osteoporosis. Hypoxia induces hypoxia inducible factor 1α gene...

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Detalles Bibliográficos
Autores principales:	Camacho-Cardenosa, Marta, Quesada-Gómez, José Manuel, Camacho-Cardenosa, Alba, Leal, Alejo, Dorado, Gabriel, Torrecillas-Baena, Bárbara, Casado-Díaz, Antonio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Baishideng Publishing Group Inc 2020
Materias:	Basic Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789125/ https://www.ncbi.nlm.nih.gov/pubmed/33505607 http://dx.doi.org/10.4252/wjsc.v12.i12.1667

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