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Presence of a mutation in PSEN1 or PSEN2 gene is associated with an impaired brain endothelial cell phenotype in vitro

BACKGROUND: Alzheimer’s disease (AD) is the most common form of neurodegenerative disease. It is an irreversible condition marked by irreversible cognitive loss, commonly attributed to the loss of hippocampal neurons due to the formation of senile plaques and neurofibrillary tangles. Although the sp...

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Detalles Bibliográficos
Autores principales:	Raut, Snehal, Patel, Ronak, Al-Ahmad, Abraham J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789219/ https://www.ncbi.nlm.nih.gov/pubmed/33413468 http://dx.doi.org/10.1186/s12987-020-00235-y

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