Cargando…

Overexpression of microRNA-29b inhibits epithelial-mesenchymal transition and angiogenesis of colorectal cancer through the ETV4/ERK/EGFR axis

BACKGROUND: Recent studies have reported the involvement of microRNA-29 (miR-29) family members in human cancers through their ability to regulate cellular functions. The present study investigated biological function of miR-29b in colorectal cancer (CRC). METHODS: CRC tissues and adjacent normal ti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Leng, Yin, Chen, Zhixian, Ding, Hui, Zhao, Xiaoxu, Qin, Li, Pan, Yunlong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789299/ https://www.ncbi.nlm.nih.gov/pubmed/33407520 http://dx.doi.org/10.1186/s12935-020-01700-2

Ejemplares similares

Overexpression of microRNA-367 inhibits angiogenesis in ovarian cancer by downregulating the expression of LPA1
por: Zheng, Qingling, et al.
Publicado: (2020)

Water-pipe smoking promotes epithelial–mesenchymal transition and invasion of human breast cancer cells via ERK1/ERK2 pathways
por: Sadek, Khaled W., et al.
Publicado: (2018)

MiR-218 regulates epithelial–mesenchymal transition and angiogenesis in colorectal cancer via targeting CTGF
por: Lun, Weijian, et al.
Publicado: (2018)

Inactivation of the Wnt/β-catenin signaling pathway underlies inhibitory role of microRNA-129-5p in epithelial–mesenchymal transition and angiogenesis of prostate cancer by targeting ZIC2
por: Jiang, Zhenming, et al.
Publicado: (2019)

Capicua suppresses colorectal cancer progression via repression of ETV4 expression
por: Lee, Jeon-Soo, et al.
Publicado: (2020)

HNRNPA2B1 regulates the epithelial–mesenchymal transition in pancreatic cancer cells through the ERK/snail signalling pathway
por: Dai, Shengjie, et al.
Publicado: (2017)

Increased ETV4 expression correlates with estrogen-enhanced proliferation and invasiveness of cholangiocarcinoma cells
por: Singsuksawat, Ekapot, et al.
Publicado: (2018)

MicroRNA-133b/EGFR axis regulates esophageal squamous cell carcinoma metastases by suppressing anoikis resistance and anchorage-independent growth
por: Zhu, Jin-Feng, et al.
Publicado: (2018)

Glioma exosomal microRNA-148a-3p promotes tumor angiogenesis through activating the EGFR/MAPK signaling pathway via inhibiting ERRFI1
por: Wang, Meng, et al.
Publicado: (2020)

Overexpression of ETV4 is oncogenic in prostate cells through promotion of both cell proliferation and epithelial to mesenchymal transition
por: Pellecchia, A, et al.
Publicado: (2012)

TEAD4 overexpression promotes epithelial-mesenchymal transition and associates with aggressiveness and adverse prognosis in head neck squamous cell carcinoma
por: Zhang, Wei, et al.
Publicado: (2018)

SIRT6/HIF-1α axis promotes papillary thyroid cancer progression by inducing epithelial–mesenchymal transition
por: Yang, Zhou, et al.
Publicado: (2019)

MicroRNA-23a regulates epithelial-to-mesenchymal transition in endometrial endometrioid adenocarcinoma by targeting SMAD3
por: Liu, Ping, et al.
Publicado: (2016)

The VIM-AS1/miR-655/ZEB1 axis modulates bladder cancer cell metastasis by regulating epithelial–mesenchymal transition
por: Xiong, Yaoyao, et al.
Publicado: (2021)

Overexpressed GATA3 enhances the sensitivity of colorectal cancer cells to oxaliplatin through regulating MiR-29b
por: Wang, Wei, et al.
Publicado: (2020)

MicroRNA-10b regulates epithelial–mesenchymal transition by modulating KLF4/KLF11/Smads in hepatocellular carcinoma
por: Hujie, Gulibaha, et al.
Publicado: (2018)

MicroRNA-93-5p promotes epithelial-mesenchymal transition in gastric cancer by repressing tumor suppressor AHNAK expression
por: Shen, Erdong, et al.
Publicado: (2020)

lncRNA TUG1 modulates proliferation, apoptosis, invasion, and angiogenesis via targeting miR-29b in trophoblast cells
por: Li, Qian, et al.
Publicado: (2019)

Overexpression of lncRNA HOXA11-AS promotes cell epithelial–mesenchymal transition by repressing miR-200b in non-small cell lung cancer
por: Chen, Jian-Hui, et al.
Publicado: (2017)

The ERK MAP kinase-PEA3/ETV4-MMP-1 axis is operative in oesophageal adenocarcinoma
por: Keld, Richard, et al.
Publicado: (2010)

Specific distribution of overexpressed aurora B kinase in interphase normal epithelial cells
por: Abdullah, Ash-shafie, et al.
Publicado: (2005)

Overexpression of mircoRNA-137 inhibits cervical cancer cell invasion, migration and epithelial–mesenchymal transition by suppressing the TGF-β/smad pathway via binding to GREM1
por: Miao, Hui, et al.
Publicado: (2019)

Metformin inhibition of neuroblastoma cell proliferation is differently modulated by cell differentiation induced by retinoic acid or overexpression of NDM29 non-coding RNA
por: Costa, Delfina, et al.
Publicado: (2014)

Downregulation of miR-29c promotes muscle wasting by modulating the activity of leukemia inhibitory factor in lung cancer cachexia
por: Xie, Kairu, et al.
Publicado: (2021)

Overexpression of Rab11-FIP2 in colorectal cancer cells promotes tumor migration and angiogenesis through increasing secretion of PAI-1
por: Dong, Wenjie, et al.
Publicado: (2018)

C-phycocyanin inhibits epithelial-to-mesenchymal transition in Caski cells
por: Ji, Huanhuan, et al.
Publicado: (2020)

LncRNA NEAT1 promotes proliferation, migration, invasion and epithelial-mesenchymal transition process in TGF-β2-stimulated lens epithelial cells through regulating the miR-486-5p/SMAD4 axis
por: Wang, Huajun, et al.
Publicado: (2020)

Epigallocatechin-3-gallate inhibits the growth and increases the apoptosis of human thyroid carcinoma cells through suppression of EGFR/RAS/RAF/MEK/ERK signaling pathway
por: Wu, Dongdong, et al.
Publicado: (2019)

Macrophages-derived exosomal lncRNA LIFR-AS1 promotes osteosarcoma cell progression via miR-29a/NFIA axis
por: Zhang, Hongliang, et al.
Publicado: (2021)

The m6A methyltransferase METTL3 controls epithelial-mesenchymal transition, migration and invasion of breast cancer through the MALAT1/miR-26b/HMGA2 axis
por: Zhao, Chengpeng, et al.
Publicado: (2021)

SNHG29 regulates miR-223-3p/CTNND1 axis to promote glioblastoma progression via Wnt/β-catenin signaling pathway
por: Han, Lizhang, et al.
Publicado: (2019)

Hypoxia-mediated YTHDF2 overexpression promotes lung squamous cell carcinoma progression by activation of the mTOR/AKT axis
por: Xu, Peng, et al.
Publicado: (2022)

Identification of collagen genes related to immune infiltration and epithelial-mesenchymal transition in glioma
por: Yin, Wen, et al.
Publicado: (2021)

Integrated analyses of microRNA-29 family and the related combination biomarkers demonstrate their widespread influence on risk, recurrence, metastasis and survival outcome in colorectal cancer
por: Peng, Qiliang, et al.
Publicado: (2019)

Role of XIAP gene overexpressed bone marrow mesenchymal stem cells in the treatment of cerebral injury in rats with cerebral palsy
por: Deng, Wenjing, et al.
Publicado: (2019)

Pepsin promotes IL-8 signaling-induced epithelial–mesenchymal transition in laryngeal carcinoma
por: Tan, Jia-Jie, et al.
Publicado: (2019)

Absence of EpCAM in cervical cancer cells is involved in sluginduced epithelial‐mesenchymal transition
por: Liu, Xian, et al.
Publicado: (2021)

LncRNA LIFR-AS1 promotes proliferation and invasion of gastric cancer cell via miR-29a-3p/COL1A2 axis
por: Pan, Haiyan, et al.
Publicado: (2021)

Specific and redundant activities of ETV1 and ETV4 in prostate cancer aggressiveness revealed by co-overexpression cellular contexts
por: Mesquita, Diana, et al.
Publicado: (2015)

MicroRNA-7 Inhibits Tumor Metastasis and Reverses Epithelial-Mesenchymal Transition through AKT/ERK1/2 Inactivation by Targeting EGFR in Epithelial Ovarian Cancer
por: Zhou, Xingchen, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_3edss8mi3mktma3mu1ciumft65