Cargando…

Chromatin accessibility maps provide evidence of multilineage gene priming in hematopoietic stem cells

Hematopoietic stem cells (HSCs) have the capacity to differentiate into vastly different types of mature blood cells. The epigenetic mechanisms regulating the multilineage ability, or multipotency, of HSCs are not well understood. To test the hypothesis that cis-regulatory elements that control fate...

Descripción completa

Detalles Bibliográficos
Autores principales: Martin, Eric W., Krietsch, Jana, Reggiardo, Roman E., Sousae, Rebekah, Kim, Daniel H., Forsberg, E. Camilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789351/
https://www.ncbi.nlm.nih.gov/pubmed/33407811
http://dx.doi.org/10.1186/s13072-020-00377-1