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Chromatin accessibility maps provide evidence of multilineage gene priming in hematopoietic stem cells
Hematopoietic stem cells (HSCs) have the capacity to differentiate into vastly different types of mature blood cells. The epigenetic mechanisms regulating the multilineage ability, or multipotency, of HSCs are not well understood. To test the hypothesis that cis-regulatory elements that control fate...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789351/ https://www.ncbi.nlm.nih.gov/pubmed/33407811 http://dx.doi.org/10.1186/s13072-020-00377-1 |