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Modified silicone stent for the treatment of post-surgical bronchopleural fistula: a clinical observation of 17 cases

BACKGROUND: Bronchopleural fistula is a rare but life-threatening event with limited therapeutic options. We aimed to investigate the efficacy and safety of the modified silicone stent in patients with post-surgical bronchopleural fistula. METHODS: Between March 2016 and April 2020, we retrospective...

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Autores principales: Zeng, Junli, Wu, Xuemei, Chen, Zhide, Zhang, Meihua, Ke, Mingyao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789393/
https://www.ncbi.nlm.nih.gov/pubmed/33407326
http://dx.doi.org/10.1186/s12890-020-01372-8
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author Zeng, Junli
Wu, Xuemei
Chen, Zhide
Zhang, Meihua
Ke, Mingyao
author_facet Zeng, Junli
Wu, Xuemei
Chen, Zhide
Zhang, Meihua
Ke, Mingyao
author_sort Zeng, Junli
collection PubMed
description BACKGROUND: Bronchopleural fistula is a rare but life-threatening event with limited therapeutic options. We aimed to investigate the efficacy and safety of the modified silicone stent in patients with post-surgical bronchopleural fistula. METHODS: Between March 2016 and April 2020, we retrospectively reviewed the records of 17 patients with bronchopleural fistula and who underwent bronchoscopic placement of the Y-shaped silicone stent. The rate of initial success, clinical success and clinical cure, and complications were analyzed. RESULTS: Stent placement was successful in 16 patients in the first attempt (initial success rate: 94.1%). The median follow-up time was 107 (range, 5–431) days. All patients achieved amelioration of respiratory symptoms. The clinical success rate was 76.5%. Of the 14 patients with empyema, the daily drainage was progressively decreased in 11 patients, and empyema completely disappeared in six patients. Seven stents were removed during follow-up: four (26.7%) for the cure of fistula, two for severe proliferation of granulomatous tissue and one for stent dislocation. No severe adverse events (i.e. massive hemoptysis, suture dehiscence) took place. Seven patients died (due to progression of malignancy, uncontrolled infection, myocardial infarction and left heart failure). CONCLUSIONS: The modified silicone stent may be an effective and safe option for patients with post-surgical bronchopleural fistula patients in whom conventional therapy is contraindicated.
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spelling pubmed-77893932021-01-07 Modified silicone stent for the treatment of post-surgical bronchopleural fistula: a clinical observation of 17 cases Zeng, Junli Wu, Xuemei Chen, Zhide Zhang, Meihua Ke, Mingyao BMC Pulm Med Research Article BACKGROUND: Bronchopleural fistula is a rare but life-threatening event with limited therapeutic options. We aimed to investigate the efficacy and safety of the modified silicone stent in patients with post-surgical bronchopleural fistula. METHODS: Between March 2016 and April 2020, we retrospectively reviewed the records of 17 patients with bronchopleural fistula and who underwent bronchoscopic placement of the Y-shaped silicone stent. The rate of initial success, clinical success and clinical cure, and complications were analyzed. RESULTS: Stent placement was successful in 16 patients in the first attempt (initial success rate: 94.1%). The median follow-up time was 107 (range, 5–431) days. All patients achieved amelioration of respiratory symptoms. The clinical success rate was 76.5%. Of the 14 patients with empyema, the daily drainage was progressively decreased in 11 patients, and empyema completely disappeared in six patients. Seven stents were removed during follow-up: four (26.7%) for the cure of fistula, two for severe proliferation of granulomatous tissue and one for stent dislocation. No severe adverse events (i.e. massive hemoptysis, suture dehiscence) took place. Seven patients died (due to progression of malignancy, uncontrolled infection, myocardial infarction and left heart failure). CONCLUSIONS: The modified silicone stent may be an effective and safe option for patients with post-surgical bronchopleural fistula patients in whom conventional therapy is contraindicated. BioMed Central 2021-01-06 /pmc/articles/PMC7789393/ /pubmed/33407326 http://dx.doi.org/10.1186/s12890-020-01372-8 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Zeng, Junli
Wu, Xuemei
Chen, Zhide
Zhang, Meihua
Ke, Mingyao
Modified silicone stent for the treatment of post-surgical bronchopleural fistula: a clinical observation of 17 cases
title Modified silicone stent for the treatment of post-surgical bronchopleural fistula: a clinical observation of 17 cases
title_full Modified silicone stent for the treatment of post-surgical bronchopleural fistula: a clinical observation of 17 cases
title_fullStr Modified silicone stent for the treatment of post-surgical bronchopleural fistula: a clinical observation of 17 cases
title_full_unstemmed Modified silicone stent for the treatment of post-surgical bronchopleural fistula: a clinical observation of 17 cases
title_short Modified silicone stent for the treatment of post-surgical bronchopleural fistula: a clinical observation of 17 cases
title_sort modified silicone stent for the treatment of post-surgical bronchopleural fistula: a clinical observation of 17 cases
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789393/
https://www.ncbi.nlm.nih.gov/pubmed/33407326
http://dx.doi.org/10.1186/s12890-020-01372-8
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