Cargando…

Mutation profile of non-small cell lung cancer revealed by next generation sequencing

BACKGROUND: Precision therapy for lung cancer requires comprehensive genomic analyses. Specific effects of targeted therapies have been reported in Asia populations, including Taiwanese, but genomic studies have rarely been performed in these populations. METHOD: We enrolled 72 patients with non-sma...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chang, Ya-Sian, Tu, Siang-Jyun, Chen, Yu-Chia, Liu, Ting-Yuan, Lee, Ya-Ting, Yen, Ju-Chen, Fang, Hsin-Yuan, Chang, Jan-Gowth
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789556/ https://www.ncbi.nlm.nih.gov/pubmed/33407425 http://dx.doi.org/10.1186/s12931-020-01608-5

Ejemplares similares

The Fusion Gene Landscape in Taiwanese Patients with Non-Small Cell Lung Cancer
por: Chang, Ya-Sian, et al.
Publicado: (2021)

Mutation Analysis of Second Primary Tumors in Oral Cancer in Taiwanese Patients through Next-Generation Sequencing
por: Liu, Ting-Yuan, et al.
Publicado: (2022)

Genome-Wide Analysis of Prognostic Alternative Splicing Signature and Splicing Factors in Lung Adenocarcinoma
por: Chang, Ya-Sian, et al.
Publicado: (2020)

Metatranscriptomic Analysis of Human Lung Metagenomes from Patients with Lung Cancer
por: Chang, Ya-Sian, et al.
Publicado: (2021)

Next-generation sequencing profiling of mitochondrial genomes in gout
por: Tseng, Chia-Chun, et al.
Publicado: (2018)

Dysregulation of Immune Cell Subpopulations in Atypical Hemolytic Uremic Syndrome
por: Chen, I-Ru, et al.
Publicado: (2023)

Comprehensive Analysis and Drug Modulation of Human Endogenous Retrovirus in Hepatocellular Carcinomas
por: Chang, Ya-Sian, et al.
Publicado: (2023)

Single-cell RNA sequencing of immune cells in patients with acute gout
por: Chang, Jan-Gowth, et al.
Publicado: (2022)

Whole genome and RNA sequencing analyses for 254 Taiwanese hepatocellular carcinomas
por: Chang, Ya-Sian, et al.
Publicado: (2023)

Exploring RNA modifications, editing, and splicing changes in hyperuricemia and gout
por: Huang, Chung-Ming, et al.
Publicado: (2022)

Down-regulated and Commonly mutated ALPK1 in Lung and Colorectal Cancers
por: Liao, Hsien-Feng, et al.
Publicado: (2016)

Male-Specific Long Noncoding RNA TTTY15 Inhibits Non-Small Cell Lung Cancer Proliferation and Metastasis via TBX4
por: Lai, I-Lu, et al.
Publicado: (2019)

4β-Hydroxywithanolide E Modulates Alternative Splicing of Apoptotic Genes in Human Hepatocellular Carcinoma Huh-7 Cells
por: Lee, Chien-Chin, et al.
Publicado: (2017)

Long noncoding RNA MIAT promotes non-small cell lung cancer proliferation and metastasis through MMP9 activation
por: Lai, I-Lu, et al.
Publicado: (2017)

Construction and Validation of a Prognostic Gene-Based Model for Overall Survival Prediction in Hepatocellular Carcinoma Using an Integrated Statistical and Bioinformatic Approach
por: Dessie, Eskezeia Yihunie, et al.
Publicado: (2021)

Molecular Classification of Hepatocellular Carcinoma Using Wnt–Hippo Signaling Pathway-Related Genes
por: Chang, Ya-Sian, et al.
Publicado: (2022)

Systematic Analysis of Transcriptomic Profile of Chondrocytes in Osteoarthritic Knee Using Next-Generation Sequencing and Bioinformatics
por: Chen, Yi-Jen, et al.
Publicado: (2018)

Rapid detection of epidermal growth factor receptor mutations with multiplex PCR and primer extension in lung cancer
por: Lin, Ching-Hsiung, et al.
Publicado: (2010)

Long noncoding RNA TUG1 is downregulated in non-small cell lung cancer and can regulate CELF1 on binding to PRC2
por: Lin, Pei-Chin, et al.
Publicado: (2016)

Pathway Mutations in Breast Cancer Using Whole-Exome Sequencing
por: Chang, Ya-Sian, et al.
Publicado: (2020)

Systematic Analysis of Differential Expression Profile in Rheumatoid Arthritis Chondrocytes Using Next-Generation Sequencing and Bioinformatics Approaches
por: Chen, Yi-Jen, et al.
Publicado: (2018)

Identification of novel genes in aging osteoblasts using next-generation sequencing and bioinformatics
por: Chen, Yi-Jen, et al.
Publicado: (2017)

Congenital dyserythropoiesis anemia type Ia with a novel CDAN1 mutation diagnosed by whole exome sequencing
por: Lin, Pei‐Chin, et al.
Publicado: (2020)

Long Noncoding RNA NTT Context-Dependently Regulates MYB by Interacting With Activated Complex in Hepatocellular Carcinoma Cells
por: Chang, Ya-Sian, et al.
Publicado: (2021)

Muscle developmental defects in heterogeneous nuclear Ribonucleoprotein A1 knockout mice
por: Liu, Ting-Yuan, et al.
Publicado: (2017)

Fast simultaneous detection of K-RAS mutations in colorectal cancer
por: Chang, Ya-Sian, et al.
Publicado: (2009)

Prognostic Value of RNASEH2A-, CDK1-, and CD151-Related Pathway Gene Profiling for Kidney Cancers
por: Yang, Chin-An, et al.
Publicado: (2018)

Analysing the mutational status of adenomatous polyposis coli (APC) gene in breast cancer
por: Chang, Ya-Sian, et al.
Publicado: (2016)

Polygenic risk score trend and new variants on chromosome 1 are associated with male gout in genome-wide association study
por: Chang, Ya-Sian, et al.
Publicado: (2022)

Deduction of Novel Genes Potentially Involved in Osteoblasts of Rheumatoid Arthritis Using Next-Generation Sequencing and Bioinformatic Approaches
por: Chen, Yi-Jen, et al.
Publicado: (2017)

Alternative splicing in human cancer cells is modulated by the amiloride derivative 3,5‐diamino‐6‐chloro‐N‐(N‐(2,6‐dichlorobenzoyl)carbamimidoyl)pyrazine‐2‐carboxide
por: Lee, Chien‐Chin, et al.
Publicado: (2019)

Multi-omics profiling reveals microRNA-mediated insulin signaling networks
por: Lin, Yang-Chi-Dung, et al.
Publicado: (2020)

Next-Generation Sequencing Profiles of the Methylome and Transcriptome in Peripheral Blood Mononuclear Cells of Rheumatoid Arthritis
por: Tseng, Chia-Chun, et al.
Publicado: (2019)

Transcribed pseudogene ψPPM1K generates endogenous siRNA to suppress oncogenic cell growth in hepatocellular carcinoma
por: Chan, Wen-Ling, et al.
Publicado: (2013)

Chromosomal microarray and whole‐exome sequence analysis in Taiwanese patients with autism spectrum disorder
por: Chang, Ya‐Sian, et al.
Publicado: (2019)

Transcriptome profiling of the fifth-stage larvae of Angiostrongylus cantonensis by next-generation sequencing
por: Wang, Lian-Chen, et al.
Publicado: (2013)

Tumor mutation burden derived from small next generation sequencing targeted gene panel as an initial screening method
por: Tang, Yuan, et al.
Publicado: (2020)

Detection of Somatic Mutations in Exome Sequencing of Tumor-only Samples
por: Hsu, Yu-Chin, et al.
Publicado: (2017)

Differential expression profiles of the transcriptome in bone marrow-derived cells in lung cancer revealed by next generation sequencing and bioinformatics
por: Chang, Wei-An, et al.
Publicado: (2019)

Next generation probiotics in disease amelioration
por: Chang, Chih-Jung, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_85inh6sac3sdtg4u2ue9up295a