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Global knockdown of glutamate decarboxylase 67 elicits emotional abnormality in mice
Reduced expression of glutamate decarboxylase 67 (GAD67), encoded by the Gad1 gene, is a consistent finding in postmortem brains of patients with several psychiatric disorders, including schizophrenia, bipolar disorder and major depressive disorder. The dysfunction of GAD67 in the brain is implicate...
Autores principales: | Miyata, Shigeo, Kakizaki, Toshikazu, Fujihara, Kazuyuki, Obinata, Hideru, Hirano, Touko, Nakai, Junichi, Tanaka, Mika, Itohara, Shigeyoshi, Watanabe, Masahiko, Tanaka, Kenji F., Abe, Manabu, Sakimura, Kenji, Yanagawa, Yuchio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789591/ https://www.ncbi.nlm.nih.gov/pubmed/33413507 http://dx.doi.org/10.1186/s13041-020-00713-2 |
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