Investigation of interleukin-2-mediated changes in blood pressure, fetal growth restriction, and innate immune activation in normal pregnant rats and in a preclinical rat model of preeclampsia

Two important clinical features of preeclampsia (PE) are hypertension and fetal growth restriction. The reduced uterine perfusion pressure (RUPP) preclinical rat model of PE exhibits both of these features. Moreover, RUPP and PE women have elevated vasoconstrictor peptide endothelin-1 (ET-1) and inf...

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Detalles Bibliográficos
Autores principales: Cunningham, Mark W., Amaral, Lorena M., Campbell, Nathan E., Cornelius, Denise C., Ibrahim, Tarek, Vaka, Venkata Ramana, LaMarca, Babbette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789596/
https://www.ncbi.nlm.nih.gov/pubmed/33407826
http://dx.doi.org/10.1186/s13293-020-00345-0

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