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Synergism between the phosphatidylinositol 3-kinase p110β isoform inhibitor AZD6482 and the mixed lineage kinase 3 inhibitor URMC-099 on the blockade of glioblastoma cell motility and focal adhesion formation

BACKGROUND: Glioblastoma multiforme, the most aggressive and malignant primary brain tumor, is characterized by rapid growth and extensive infiltration to neighboring normal brain parenchyma. Our previous studies delineated a crosstalk between PI3K/Akt and JNK signaling pathways, and a moderate anti...

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Detalles Bibliográficos
Autores principales:	Zhao, Hua-fu, Wu, Chang-peng, Zhou, Xiu-ming, Diao, Peng-yu, Xu, Yan-wen, Liu, Jing, Wang, Jing, Huang, Xian-jian, Liu, Wen-lan, Chen, Zhong-ping, Huang, Guo-dong, Li, Wei-ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789614/ https://www.ncbi.nlm.nih.gov/pubmed/33407478 http://dx.doi.org/10.1186/s12935-020-01728-4

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