Homoharringtonine inhibits fibroblasts proliferation, extracellular matrix production and reduces surgery-induced knee arthrofibrosis via PI3K/AKT/mTOR pathway-mediated apoptosis

BACKGROUND: The prevention of surgery-induced intraarticular fibrosis remains a challenge following orthopedic surgery. Homoharringtonine (HHT) has been reported to have positive effects in preventing various kinds of fibrosis. However, little is known regarding its effect as well as the potential m...

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Detalles Bibliográficos
Autores principales: Sun, Yu, Dai, Jihang, Jiao, Rui, Jiang, Qing, Wang, Jingcheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789651/
https://www.ncbi.nlm.nih.gov/pubmed/33407698
http://dx.doi.org/10.1186/s13018-020-02150-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789651/
https://www.ncbi.nlm.nih.gov/pubmed/33407698
http://dx.doi.org/10.1186/s13018-020-02150-2

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