Environmental noise stress disturbs commensal microbiota homeostasis and induces oxi-inflammmation and AD-like neuropathology through epithelial barrier disruption in the EOAD mouse model

BACKGROUND: Both genetic factors and environmental hazards, including environmental noise stress, have been associated with gut microbiome that exacerbates Alzheimer’s disease (AD) pathology. However, the role and mechanism of environmental risk factors in early-onset AD (EOAD) pathogenesis remain u...

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Detalles Bibliográficos
Autores principales: Chi, Huimin, Cao, Wa, Zhang, Ming, Su, Donghong, Yang, Honglian, Li, Zhe, Li, Chao, She, Xiaojun, Wang, Kun, Gao, Xiujie, Ma, Kefeng, Zheng, Pengfang, Li, Xiaofang, Cui, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789697/
https://www.ncbi.nlm.nih.gov/pubmed/33407614
http://dx.doi.org/10.1186/s12974-020-02053-3

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