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Microglial inflammation after chronic spinal cord injury is enhanced by reactive astrocytes via the fibronectin/β1 integrin pathway
BACKGROUND: After spinal cord injury (SCI), glial scarring is mainly formed around the lesion and inhibits axon regeneration. Recently, we reported that anti-β1 integrin antibody (β1Ab) had a therapeutic effect on astrocytes by preventing the induction of glial scar formation. However, the cellular...
Autores principales: | Yoshizaki, Shingo, Tamaru, Tetsuya, Hara, Masamitsu, Kijima, Ken, Tanaka, Masatake, Konno, Dai-jiro, Matsumoto, Yoshihiro, Nakashima, Yasuharu, Okada, Seiji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789752/ https://www.ncbi.nlm.nih.gov/pubmed/33407620 http://dx.doi.org/10.1186/s12974-020-02059-x |
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