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Comparisons of neuroinflammation, microglial activation, and degeneration of the locus coeruleus-norepinephrine system in APP/PS1 and aging mice

BACKGROUND: The role of microglia in Alzheimer’s disease (AD) pathogenesis is becoming increasingly important, as activation of these cell types likely contributes to both pathological and protective processes associated with all phases of the disease. During early AD pathogenesis, one of the first...

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Detalles Bibliográficos
Autores principales: Cao, Song, Fisher, Daniel W., Rodriguez, Guadalupe, Yu, Tian, Dong, Hongxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789762/
https://www.ncbi.nlm.nih.gov/pubmed/33407625
http://dx.doi.org/10.1186/s12974-020-02054-2