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Risk assessment of acute kidney injury following cardiopulmonary bypass
BACKGROUND: Acute kidney injury (AKI) is a frequent and serious complication of cardiac surgery, associated with a high incidence of morbidity and mortality. Although the RIFLE criteria serve as a prominent tool to identify patients at high risk of AKI, an optimized diagnosis model in clinical pract...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789772/ https://www.ncbi.nlm.nih.gov/pubmed/33407652 http://dx.doi.org/10.1186/s13019-020-01382-x |
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author | Wittlinger, Thomas Maus, Martin Kutschka, Ingo Baraki, Hassina Friedrich, Martin G. |
author_facet | Wittlinger, Thomas Maus, Martin Kutschka, Ingo Baraki, Hassina Friedrich, Martin G. |
author_sort | Wittlinger, Thomas |
collection | PubMed |
description | BACKGROUND: Acute kidney injury (AKI) is a frequent and serious complication of cardiac surgery, associated with a high incidence of morbidity and mortality. Although the RIFLE criteria serve as a prominent tool to identify patients at high risk of AKI, an optimized diagnosis model in clinical practice is desired. METHODS: Based on the SOP-criteria, 365 patients (10%) developed AKI following surgery and were subjected to RRT. In contrast, the incidence of AKI, defined according to the RIFLE criteria, was only 7% (n = 251 patients). Prominent risk factors identified by SOP were patients’ sex, valve and combined valve and bypass surgery, deep hypothermia, use of intra-aortic balloon pump (IABP) and previous coronary interventions. Ischemia, reperfusion, blood loss and surgery time also served as significant risk factors for patient evaluated by SOP. RESULTS: Risk assessment by RIFLE differed in as much as most patients with normothermia and those receiving only cardiovascular bypass developed AKI. However, patients’ sex and valve surgery did not serve as a risk factor. CONCLUSION: Evaluation of patients by the RIFLE versus SOP criteria yielded different results with more AKI patients detected by SOP. Based on the present data, it is concluded that patients may not prone to AKI when surgery and ischemia time will be kept short, when blood loss is mitigated to a minimum and when surgery is performed under non-hypothermic conditions. |
format | Online Article Text |
id | pubmed-7789772 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-77897722021-01-07 Risk assessment of acute kidney injury following cardiopulmonary bypass Wittlinger, Thomas Maus, Martin Kutschka, Ingo Baraki, Hassina Friedrich, Martin G. J Cardiothorac Surg Research Article BACKGROUND: Acute kidney injury (AKI) is a frequent and serious complication of cardiac surgery, associated with a high incidence of morbidity and mortality. Although the RIFLE criteria serve as a prominent tool to identify patients at high risk of AKI, an optimized diagnosis model in clinical practice is desired. METHODS: Based on the SOP-criteria, 365 patients (10%) developed AKI following surgery and were subjected to RRT. In contrast, the incidence of AKI, defined according to the RIFLE criteria, was only 7% (n = 251 patients). Prominent risk factors identified by SOP were patients’ sex, valve and combined valve and bypass surgery, deep hypothermia, use of intra-aortic balloon pump (IABP) and previous coronary interventions. Ischemia, reperfusion, blood loss and surgery time also served as significant risk factors for patient evaluated by SOP. RESULTS: Risk assessment by RIFLE differed in as much as most patients with normothermia and those receiving only cardiovascular bypass developed AKI. However, patients’ sex and valve surgery did not serve as a risk factor. CONCLUSION: Evaluation of patients by the RIFLE versus SOP criteria yielded different results with more AKI patients detected by SOP. Based on the present data, it is concluded that patients may not prone to AKI when surgery and ischemia time will be kept short, when blood loss is mitigated to a minimum and when surgery is performed under non-hypothermic conditions. BioMed Central 2021-01-06 /pmc/articles/PMC7789772/ /pubmed/33407652 http://dx.doi.org/10.1186/s13019-020-01382-x Text en © The Author(s) 2021 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Article Wittlinger, Thomas Maus, Martin Kutschka, Ingo Baraki, Hassina Friedrich, Martin G. Risk assessment of acute kidney injury following cardiopulmonary bypass |
title | Risk assessment of acute kidney injury following cardiopulmonary bypass |
title_full | Risk assessment of acute kidney injury following cardiopulmonary bypass |
title_fullStr | Risk assessment of acute kidney injury following cardiopulmonary bypass |
title_full_unstemmed | Risk assessment of acute kidney injury following cardiopulmonary bypass |
title_short | Risk assessment of acute kidney injury following cardiopulmonary bypass |
title_sort | risk assessment of acute kidney injury following cardiopulmonary bypass |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789772/ https://www.ncbi.nlm.nih.gov/pubmed/33407652 http://dx.doi.org/10.1186/s13019-020-01382-x |
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