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Human-derived NLS enhance the gene transfer efficiency of chitosan
Nuclear import is considered as one of the major limitations for non-viral gene delivery systems and the incorporation of nuclear localization signals (NLS) that mediate nuclear intake can be used as a strategy to enhance internalization of exogenous DNA. In this work, human-derived endogenous NLS p...
Autores principales: | Bitoque, Diogo B., Morais, Joana, Oliveira, Ana V., Sequeira, Raquel L., Calado, Sofia M., Fortunato, Tiago M., Simão, Sónia, Rosa da Costa, Ana M., Silva, Gabriela A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789810/ https://www.ncbi.nlm.nih.gov/pubmed/33305307 http://dx.doi.org/10.1042/BSR20201026 |
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