Cycling Stem Cells Are Radioresistant and Regenerate the Intestine

A certain number of epithelial cells in intestinal crypts are DNA damage resistant and contribute to regeneration. However, the cellular mechanism underlying intestinal regeneration remains unclear. Using lineage tracing, we show that cells marked by an Msi1 reporter (Msi1(+)) are right above Lgr5(h...

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Detalles Bibliográficos
Autores principales: Sheng, Xiaole, Lin, Ziguang, Lv, Cong, Shao, Chunlei, Bi, Xueyun, Deng, Min, Xu, Jiuzhi, Guerrero-Juarez, Christian F., Li, Mengzhen, Wu, Xi, Zhao, Ran, Yang, Xu, Li, Guilin, Liu, Xiaowei, Wang, Qingyu, Nie, Qing, Cui, Wei, Gao, Shan, Zhang, Hongquan, Liu, Zhihua, Cong, Yingzi, Plikus, Maksim V., Lengner, Christopher J., Andersen, Bogi, Ren, Fazheng, Yu, Zhengquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789978/
https://www.ncbi.nlm.nih.gov/pubmed/32726617
http://dx.doi.org/10.1016/j.celrep.2020.107952

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