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A Computational Modeling Study of COVID-19 in Bangladesh

The COVID-19 pandemic has spread globally. Only three cases in Bangladesh were reported on March 8, 2020. Here, we aim to predict the epidemic progression for 1 year under different scenarios in Bangladesh. We extracted the number of daily confirmed cases from March 8 to July 20, 2020. We considered...

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Autores principales: Khan, Irtesam Mahmud, Haque, Ubydul, Kaisar, Samiha, Rahman, Mohammad Sohel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Tropical Medicine and Hygiene 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7790066/
https://www.ncbi.nlm.nih.gov/pubmed/33146109
http://dx.doi.org/10.4269/ajtmh.20-0757
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author Khan, Irtesam Mahmud
Haque, Ubydul
Kaisar, Samiha
Rahman, Mohammad Sohel
author_facet Khan, Irtesam Mahmud
Haque, Ubydul
Kaisar, Samiha
Rahman, Mohammad Sohel
author_sort Khan, Irtesam Mahmud
collection PubMed
description The COVID-19 pandemic has spread globally. Only three cases in Bangladesh were reported on March 8, 2020. Here, we aim to predict the epidemic progression for 1 year under different scenarios in Bangladesh. We extracted the number of daily confirmed cases from March 8 to July 20, 2020. We considered the suspected-infected-removed (SIR) model and performed a maximum likelihood-based grid search to determine the removal rate (ɣ). The transmission was modeled as a stochastic random walk process, and sequential Monte Carlo simulation was run 100 times with bootstrap fits to infer the transmission rate (β) and R(t). According to the simulation, the (real) peak daily incidence of 3,600 would be followed by a steady decline, reaching below 1,000 in late January 2021. Thus, the model predicted that there would still be more than 300 cases/day even after a year. However, with proper interventions, a much steeper decline would be achieved following the peak. If we apply a combined (0.8β, 1.2ɣ) intervention, there would be less than 100 cases by mid-October, only around five odd cases at the beginning of the year 2021, and zero cases in early March 2021. The predicted total number of deaths (in status quo) after 1 year would be 8,533 which would reduce to 3,577 if combined (0.8β, 1.2ɣ) intervention is applied. We have also predicted the ideal number of tests that Bangladesh should perform and based on that redid the whole simulation. The outcome, though worse, would be manageable with interventions according to the simulation.
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spelling pubmed-77900662021-01-08 A Computational Modeling Study of COVID-19 in Bangladesh Khan, Irtesam Mahmud Haque, Ubydul Kaisar, Samiha Rahman, Mohammad Sohel Am J Trop Med Hyg Articles The COVID-19 pandemic has spread globally. Only three cases in Bangladesh were reported on March 8, 2020. Here, we aim to predict the epidemic progression for 1 year under different scenarios in Bangladesh. We extracted the number of daily confirmed cases from March 8 to July 20, 2020. We considered the suspected-infected-removed (SIR) model and performed a maximum likelihood-based grid search to determine the removal rate (ɣ). The transmission was modeled as a stochastic random walk process, and sequential Monte Carlo simulation was run 100 times with bootstrap fits to infer the transmission rate (β) and R(t). According to the simulation, the (real) peak daily incidence of 3,600 would be followed by a steady decline, reaching below 1,000 in late January 2021. Thus, the model predicted that there would still be more than 300 cases/day even after a year. However, with proper interventions, a much steeper decline would be achieved following the peak. If we apply a combined (0.8β, 1.2ɣ) intervention, there would be less than 100 cases by mid-October, only around five odd cases at the beginning of the year 2021, and zero cases in early March 2021. The predicted total number of deaths (in status quo) after 1 year would be 8,533 which would reduce to 3,577 if combined (0.8β, 1.2ɣ) intervention is applied. We have also predicted the ideal number of tests that Bangladesh should perform and based on that redid the whole simulation. The outcome, though worse, would be manageable with interventions according to the simulation. The American Society of Tropical Medicine and Hygiene 2021-01 2020-11-02 /pmc/articles/PMC7790066/ /pubmed/33146109 http://dx.doi.org/10.4269/ajtmh.20-0757 Text en © The American Society of Tropical Medicine and Hygiene This is an open-access article distributed under the terms of the Creative Commons Attribution (CC-BY) License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Articles
Khan, Irtesam Mahmud
Haque, Ubydul
Kaisar, Samiha
Rahman, Mohammad Sohel
A Computational Modeling Study of COVID-19 in Bangladesh
title A Computational Modeling Study of COVID-19 in Bangladesh
title_full A Computational Modeling Study of COVID-19 in Bangladesh
title_fullStr A Computational Modeling Study of COVID-19 in Bangladesh
title_full_unstemmed A Computational Modeling Study of COVID-19 in Bangladesh
title_short A Computational Modeling Study of COVID-19 in Bangladesh
title_sort computational modeling study of covid-19 in bangladesh
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7790066/
https://www.ncbi.nlm.nih.gov/pubmed/33146109
http://dx.doi.org/10.4269/ajtmh.20-0757
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