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IL-17C contributes to NTHi-induced inflammation and lung damage in experimental COPD and is present in sputum during acute exacerbations

Neutrophilic inflammation results in loss of lung function in chronic obstructive pulmonary disease (COPD). Gram-negative bacteria, such as nontypeable Haemophilus influenzae (NTHi), trigger acute exacerbations of COPD (AECOPD) and contribute to chronic lung inflammation. The pro-inflammatory cytoki...

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Detalles Bibliográficos
Autores principales: Vella, Giovanna, Ritzmann, Felix, Wolf, Lisa, Kamyschnikov, Andreas, Stodden, Hannah, Herr, Christian, Slevogt, Hortense, Bals, Robert, Beisswenger, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7790230/
https://www.ncbi.nlm.nih.gov/pubmed/33411748
http://dx.doi.org/10.1371/journal.pone.0243484