Cargando…

IL-17C contributes to NTHi-induced inflammation and lung damage in experimental COPD and is present in sputum during acute exacerbations

Neutrophilic inflammation results in loss of lung function in chronic obstructive pulmonary disease (COPD). Gram-negative bacteria, such as nontypeable Haemophilus influenzae (NTHi), trigger acute exacerbations of COPD (AECOPD) and contribute to chronic lung inflammation. The pro-inflammatory cytoki...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vella, Giovanna, Ritzmann, Felix, Wolf, Lisa, Kamyschnikov, Andreas, Stodden, Hannah, Herr, Christian, Slevogt, Hortense, Bals, Robert, Beisswenger, Christoph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7790230/ https://www.ncbi.nlm.nih.gov/pubmed/33411748 http://dx.doi.org/10.1371/journal.pone.0243484

Ejemplares similares

The IL-17 receptor IL-17RE mediates polyIC-induced exacerbation of experimental allergic asthma
por: Vella, Giovanna, et al.
Publicado: (2020)

IL-17 Cytokines and Chronic Lung Diseases
por: Ritzmann, Felix, et al.
Publicado: (2022)

The composition of the pulmonary microbiota in sarcoidosis – an observational study
por: Becker, André, et al.
Publicado: (2019)

IL-17C-mediated innate inflammation decreases the response to PD-1 blockade in a model of Kras-driven lung cancer
por: Ritzmann, Felix, et al.
Publicado: (2019)

IL-17C and IL-17RE Promote Wound Closure in a Staphylococcus aureus-Based Murine Wound Infection Model
por: Pätzold, Linda, et al.
Publicado: (2021)

Mechanisms of corticosteroid insensitivity in COPD alveolar macrophages exposed to NTHi
por: Khalaf, Rana M., et al.
Publicado: (2017)

Sputum Bacterial and Fungal Dynamics during Exacerbations of Severe COPD
por: Su, Jin, et al.
Publicado: (2015)

Bacterial flora in the sputum and comorbidity in patients with acute exacerbations of COPD
por: Boixeda, Ramon, et al.
Publicado: (2015)

Validation of the breathlessness, cough and sputum scale to predict COPD exacerbation
por: DeVries, Rebecca, et al.
Publicado: (2016)

The sputum transcriptome better predicts COPD exacerbations after the withdrawal of inhaled corticosteroids than sputum eosinophils
por: Ditz, Benedikt, et al.
Publicado: (2021)

The Most Common Detected Bacteria in Sputum of Patients with the Acute Exacerbation of COPD
por: Cukic, Vesna
Publicado: (2013)

Sputum PGP is reduced by azithromycin treatment in patients with COPD and correlates with exacerbations
por: O'Reilly, Philip J, et al.
Publicado: (2013)

Characteristics of the sputum microbiome in COPD exacerbations and correlations between clinical indices
por: Su, Linfan, et al.
Publicado: (2022)

Sputum Cytokine Profiling in COPD: Comparison Between Stable Disease and Exacerbation
por: Barta, Imre, et al.
Publicado: (2022)

Receptor for advanced glycation endproducts (RAGE) maintains pulmonary structure and regulates the response to cigarette smoke
por: Wolf, Lisa, et al.
Publicado: (2017)

Relationships between Mucosal Antibodies, Non-Typeable Haemophilus influenzae (NTHi) Infection and Airway Inflammation in COPD
por: Staples, Karl J., et al.
Publicado: (2016)

Altered Gene Expression in Blood and Sputum in COPD Frequent Exacerbators in the ECLIPSE Cohort
por: Singh, Dave, et al.
Publicado: (2014)

Correlation between fractional exhaled nitric oxide and sputum eosinophilia in exacerbations of COPD
por: Gao, Jie, et al.
Publicado: (2017)

IgE is associated with exacerbations and lung function decline in COPD
por: Lommatzsch, Marek, et al.
Publicado: (2022)

Th17 profile in COPD exacerbations
por: Ponce-Gallegos, Marco Antonio, et al.
Publicado: (2017)

Flagellin shifts 3D bronchospheres towards mucus hyperproduction
por: Sprott, Richard F., et al.
Publicado: (2020)

Correction: Relationships between Mucosal Antibodies, Non-Typeable Haemophilus influenzae (NTHi) Infection and Airway Inflammation in COPD
por: Staples, Karl J., et al.
Publicado: (2017)

The role of NTHi colonization and infection in the pathogenesis of neutrophilic asthma
por: Zhang, Jing, et al.
Publicado: (2020)

Expression levels of induced sputum IL-8 and IL-10 and drug intervention effects in patients with acute exacerbated COPD complicated with chronic cor pulmonale at high altitude
por: FENG, ENZHI, et al.
Publicado: (2013)

MMP-9, TIMP-1 and inflammatory cells in sputum from COPD patients during exacerbation
por: Mercer, PF, et al.
Publicado: (2005)

A Sputum 6 Gene Expression Signature Predicts Inflammatory Phenotypes and Future Exacerbations of COPD
por: Baines, Katherine J, et al.
Publicado: (2020)

Low human beta-defensin-2 levels in the sputum of COPD patients are associated with the risk of exacerbations
por: Feng, Shengchuan, et al.
Publicado: (2023)

Real-life data on antibiotic prescription and sputum culture diagnostics in acute exacerbations of COPD in primary care
por: Bathoorn, Erik, et al.
Publicado: (2017)

Microbiome balance in sputum determined by PCR stratifies COPD exacerbations and shows potential for selective use of antibiotics
por: Haldar, Koirobi, et al.
Publicado: (2017)

Responsivity and Reproducibility of Sputum Inflammatory Biomarkers During COPD Exacerbation and Stable Phases – A Pilot Study
por: Ditz, B, et al.
Publicado: (2021)

The Lung Immune Response to Nontypeable Haemophilus influenzae (Lung Immunity to NTHi)
por: King, Paul T., et al.
Publicado: (2015)

In Vitro Anti-NTHi Activity of Haemophilin-Producing Strains of Haemophilus haemolyticus
por: Atto, Brianna, et al.
Publicado: (2020)

Sputum colour as a marker for bacteria in acute exacerbations of COPD: protocol for a systematic review and meta-analysis
por: Spies, Ruan, et al.
Publicado: (2021)

Analysis of sputum microbial metagenome in COPD based on exacerbation frequency and lung function: a case control study
por: Li, Wei, et al.
Publicado: (2022)

The altered sputum microbiome profile in patients with moderate and severe COPD exacerbations, compared to the healthy group in the Indian population
por: Hazra, Druti, et al.
Publicado: (2023)

Sputum-Rheology-Based Strategy for Guiding Azithromycin Prescription in COPD Patients with Frequent Exacerbations: A Randomized, Controlled Study (“COPD CARhE”)
por: Charriot, Jeremy, et al.
Publicado: (2023)

Rescue therapy for refractory status asthmaticus with updosed omalizumab adjusted for IgE level, body weight and effect
por: Slevogt, Hortense, et al.
Publicado: (2022)

Expression of the T Helper 17-Associated Cytokines IL-17A and IL-17F in Asthma and COPD
por: Doe, Camille, et al.
Publicado: (2010)

Microparticles in sputum of COPD patients: a potential biomarker of the disease?
por: Lacedonia, Donato, et al.
Publicado: (2016)

Interaction of allergic airway inflammation and innate immunity: hygiene and beyond
por: Beisswenger, Christoph, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_pnk50iqpu6tg4jq6pelis1sqms