CRISPR/Cas9-loaded stealth liposomes effectively cleared established HPV16-driven tumours in syngeneic mice

Gene-editing has raised the possibility of being able to treat or cure cancers, but key challenges remain, including efficient delivery, in vivo efficacy, and its safety profile. Ideal targets for cancer therapy are oncogenes, that when edited, cause cell death. Here, we show, using the human papill...

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Detalles Bibliográficos
Autores principales: Jubair, Luqman, Lam, Alfred K., Fallaha, Sora, McMillan, Nigel A. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7790238/
https://www.ncbi.nlm.nih.gov/pubmed/33411765
http://dx.doi.org/10.1371/journal.pone.0223288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7790238/
https://www.ncbi.nlm.nih.gov/pubmed/33411765
http://dx.doi.org/10.1371/journal.pone.0223288

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