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Temporal patterns of hospitalizations for diabetic ketoacidosis in children and adolescents

OBJECTIVES: To examine the temporal patterns of hospitalizations with diabetic ketoacidosis (DKA) in the pediatric population and their associated fiscal impact. METHODS: The Texas Inpatient Public Use Data File was used to identify hospitalizations of state residents aged 1month-19 years with a pri...

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Detalles Bibliográficos
Autores principales: Kalla Vyas, Arpita, Oud, Lavi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7790255/
https://www.ncbi.nlm.nih.gov/pubmed/33411822
http://dx.doi.org/10.1371/journal.pone.0245012
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author Kalla Vyas, Arpita
Oud, Lavi
author_facet Kalla Vyas, Arpita
Oud, Lavi
author_sort Kalla Vyas, Arpita
collection PubMed
description OBJECTIVES: To examine the temporal patterns of hospitalizations with diabetic ketoacidosis (DKA) in the pediatric population and their associated fiscal impact. METHODS: The Texas Inpatient Public Use Data File was used to identify hospitalizations of state residents aged 1month-19 years with a primary diagnosis of DKA during 2005–2014. Temporal changes of population-adjusted hospitalization rates and hospitalization volumes were examined for the whole cohort and on stratified analyses of sociodemographic attributes. Changes in the aggregate and per-hospitalization charges were assessed overall and on stratified analyses. RESULTS: There were 24,072 DKA hospitalizations during the study period. The population-adjusted hospitalization rate for the whole cohort increased from 31.3 to 35.9 per 100,000 between 2005–2006 and 2013–2014. Hospitalization volume increased by 30.2% over the same period, driven mainly by males, ethnic minorities, those with Medicaid insurance and uninsured patients. The aggregate hospital charges increased from approximately $69 million to $130 million between 2005–2006 and 2013–2014, with 66% of the rise being due to increased per-hospitalization charges. CONCLUSIONS: There was progressive rise in pediatric DKA hospitalizations over the last decade, with concurrent near-doubling of the associated fiscal footprint. Marked disparities were noted in the increasing hospitalization burden of DKA, born predominantly by racial and ethnic minorities, as well as by the underinsured and the uninsured. Further studies are needed to identify scalable preventive measures to achieve an equitable reduction of pediatric DKA events.
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spelling pubmed-77902552021-01-14 Temporal patterns of hospitalizations for diabetic ketoacidosis in children and adolescents Kalla Vyas, Arpita Oud, Lavi PLoS One Research Article OBJECTIVES: To examine the temporal patterns of hospitalizations with diabetic ketoacidosis (DKA) in the pediatric population and their associated fiscal impact. METHODS: The Texas Inpatient Public Use Data File was used to identify hospitalizations of state residents aged 1month-19 years with a primary diagnosis of DKA during 2005–2014. Temporal changes of population-adjusted hospitalization rates and hospitalization volumes were examined for the whole cohort and on stratified analyses of sociodemographic attributes. Changes in the aggregate and per-hospitalization charges were assessed overall and on stratified analyses. RESULTS: There were 24,072 DKA hospitalizations during the study period. The population-adjusted hospitalization rate for the whole cohort increased from 31.3 to 35.9 per 100,000 between 2005–2006 and 2013–2014. Hospitalization volume increased by 30.2% over the same period, driven mainly by males, ethnic minorities, those with Medicaid insurance and uninsured patients. The aggregate hospital charges increased from approximately $69 million to $130 million between 2005–2006 and 2013–2014, with 66% of the rise being due to increased per-hospitalization charges. CONCLUSIONS: There was progressive rise in pediatric DKA hospitalizations over the last decade, with concurrent near-doubling of the associated fiscal footprint. Marked disparities were noted in the increasing hospitalization burden of DKA, born predominantly by racial and ethnic minorities, as well as by the underinsured and the uninsured. Further studies are needed to identify scalable preventive measures to achieve an equitable reduction of pediatric DKA events. Public Library of Science 2021-01-07 /pmc/articles/PMC7790255/ /pubmed/33411822 http://dx.doi.org/10.1371/journal.pone.0245012 Text en © 2021 Kalla Vyas, Oud http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Kalla Vyas, Arpita
Oud, Lavi
Temporal patterns of hospitalizations for diabetic ketoacidosis in children and adolescents
title Temporal patterns of hospitalizations for diabetic ketoacidosis in children and adolescents
title_full Temporal patterns of hospitalizations for diabetic ketoacidosis in children and adolescents
title_fullStr Temporal patterns of hospitalizations for diabetic ketoacidosis in children and adolescents
title_full_unstemmed Temporal patterns of hospitalizations for diabetic ketoacidosis in children and adolescents
title_short Temporal patterns of hospitalizations for diabetic ketoacidosis in children and adolescents
title_sort temporal patterns of hospitalizations for diabetic ketoacidosis in children and adolescents
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7790255/
https://www.ncbi.nlm.nih.gov/pubmed/33411822
http://dx.doi.org/10.1371/journal.pone.0245012
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