Transcriptional profiling of pediatric cholestatic livers identifies three distinct macrophage populations

BACKGROUND & AIMS: Limited understanding of the role for specific macrophage subsets in the pathogenesis of cholestatic liver injury is a barrier to advancing medical therapy. Macrophages have previously been implicated in both the mal-adaptive and protective responses in obstructive cholestasis...

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Detalles Bibliográficos
Autores principales: Taylor, Sarah A., Chen, Shang-Yang, Gadhvi, Gaurav, Feng, Liang, Gromer, Kyle D., Abdala-Valencia, Hiam, Nam, Kiwon, Dominguez, Salina T., Montgomery, Anna B., Reyfman, Paul A., Ostilla, Lorena, Wechsler, Joshua B., Cuda, Carla M., Green, Richard M., Perlman, Harris, Winter, Deborah R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7790256/
https://www.ncbi.nlm.nih.gov/pubmed/33411796
http://dx.doi.org/10.1371/journal.pone.0244743

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