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Novel modulators of p53-signaling encoded by unknown genes of emerging viruses

The p53 transcription factor plays a key role both in cancer and in the cell-intrinsic response to infections. The ORFEOME project hypothesized that novel p53-virus interactions reside in hitherto uncharacterized, unknown, or hypothetical open reading frames (orfs) of human viruses. Hence, 172 orfs...

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Detalles Bibliográficos
Autores principales:	Alzhanova, Dina, Corcoran, Kathleen, Bailey, Aubrey G., Long, Kristin, Taft-Benz, Sharon, Graham, Rachel L., Broussard, Grant S., Heise, Mark, Neumann, Gabriele, Halfmann, Peter, Kawaoka, Yoshihiro, Baric, Ralph S., Damania, Blossom, Dittmer, Dirk P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7790267/ https://www.ncbi.nlm.nih.gov/pubmed/33411764 http://dx.doi.org/10.1371/journal.ppat.1009033

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